Paeonol
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| Names | |
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| Preferred IUPAC name
1-(2-Hydroxy-4-methoxyphenyl)ethan-1-one | |
| Other names
2'-Hydroxy-4'-methoxyacetophenone
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| Identifiers | |
3D model (
JSmol ) |
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| ChemSpider | |
ECHA InfoCard
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100.008.194 |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C9H10O3 | |
| Molar mass | 166.176 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Paeonol is a phenolic compound found in
Paeonia suffruticosa (moutan cortex),[3][4] in Arisaema erubescens,[5] and in Dioscorea japonica.[6] It is a chemical compound found in some traditional Chinese medicines.[7]
Biological effects
A number of biological effects of paeonol cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease.[8] Paeonol also reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured rats.[9]
Paeonol shows
TNF-α.[11]
Paeonol has weak
MAO-B inhibiting effects with IC50 values of 54.6 μM and 42.5 μM respectively.[12]
Metal complex
Metal complexes of paeonol shows tetrahedral and octahedral coordination geometry in the absence and presence of solvent pyridine respectively.[13]