Phenylbiguanide

Phenylbiguanide

Legal status
Legal status	UN: Unscheduled
Identifiers
IUPAC name 1-Phenylbiguanide
JSmol)	Interactive image
Melting point	135–142 °C (275–288 °F)
SMILES c1ccc(cc1)NC(=N)NC(=N)N
InChI InChI=1S/C8H11N5/c9-7(10)13-8(11)12-6-4-2-1-3-5-6/h1-5H,(H6,9,10,11,12,13) Key:CUQCMXFWIMOWRP-UHFFFAOYSA-N

Phenylbiguanide (PBG) is a 5-HT3 agonist used to study the role of 5-HT3 receptors in the central nervous system.^[1] It has been found to trigger dopamine release in the nucleus accumbens of rats.^[2]

Derivatives

• Phenylbiguanide is used to make amanozine and benfosformin.^{[citation needed]}

References