Prinomastat

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Prinomastat
Clinical data
ATC code
  • None
Pharmacokinetic data
Elimination half-life1–5 hours[1]
Identifiers
  • (3S)-N-Hydroxy-2,2-dimethyl-4-(4-pyridin-4-yloxyphenyl)sulfonylthiomorpholine-3-carboxamide
JSmol)
  • CC1([C@@H](N(CCS1)S(=O)(=O)C2=CC=C(C=C2)OC3=CC=NC=C3)C(=O)NO)C
  • InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(11-12-27-18)28(24,25)15-5-3-13(4-6-15)26-14-7-9-19-10-8-14/h3-10,16,23H,11-12H2,1-2H3,(H,20,22)/t16-/m0/s1
  • Key:YKPYIPVDTNNYCN-INIZCTEOSA-N

Prinomastat (code name AG-3340) is a

non-small cell lung cancer (NSCLC), in combination with gemcitabine chemotherapy. However, it was discovered that Prinomastat did not improve the outcome of chemotherapy in advanced non-small-cell lung cancer.[1][2]

References

  1. ^
    PMID 15681529
    .
  2. PMID 14871966
    .
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