SLC45A4
| SLC45A4 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 8: 141.21 – 141.31 Mb | Chr 15: 73.45 – 73.52 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
SLC45A4 is a member of the SLC45 family of
solute carriers. Analysis of the protein function in a recombinant yeast expression assay show that it can: (i) transport a disaccharide, sucrose, as well simple sugars such as glucose and fructose (ii) perform secondary active transport in a proton-dependent manner.[5]
It is associated with sugar transport in the
spermatozoa.[6] Additionally, it has been identified as a necessary component in the cell death caused of the compound paraquat.[7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000022567 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000079020 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 25164149.
- PMID 28689241.
- PMID 29058724.
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