Schlenk equilibrium
The Schlenk equilibrium, named after its discoverer Wilhelm Schlenk, is a chemical equilibrium taking place in solutions of Grignard reagents[1][2] and Hauser bases[3][4]
- 2 RMgX ⇌ MgX2 + MgR2
The process described is an equilibrium between two equivalents of an alkyl or aryl magnesium halide on the left of the equation and on the right side, one equivalent of the di
dimers and higher oligomers, especially at high concentration. Alkyl magnesium chlorides in ether are present as dimers.[5]
The position of the equilibrium is influenced by solvent, temperature, and the nature of the various substituents. It is known that magnesium center in Grignard reagents typically coordinates two molecules of ether such as diethyl ether or
dioxane to such solutions, however, leads to precipitation of the coordination polymers MgX2(μ-dioxane)2,[6] driving the equilibrium completely to the right. [7]
The dialkylmagnesium compounds are popular in the synthesis of organometallic compounds.
References
- .
- ISBN 0-471-99908-3
- ^ Neufeld, R.: DOSY External Calibration Curve Molecular Weight Determination as a Valuable Methodology in Characterizing Reactive Intermediates in Solution. In: eDiss, Georg-August-Universität Göttingen. 2016.
- PMID 27011251.
- ISBN 0-471-85472-7
- PMID 31328293.
- )