Solute carrier organic anion transporter family member 4c1
| SLCO4C1 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 5: 102.23 – 102.3 Mb | Chr 1: 96.74 – 96.8 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Solute carrier organic anion transporter family member 4C1 is a
anions for elimination in the urine. The drug digoxin is an important substrate of this transporter.[5][6]
Function
SLCO4C1 belongs to the organic anion transporter (OATP) family. OATPs are involved in the membrane transport of bile acids, conjugated steroids, thyroid hormone, eicosanoids, peptides, and numerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed 14993604]).
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000173930 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040693 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 14993604.
- ^ "Entrez Gene: Solute carrier organic anion transporter family member 4C1". Retrieved 2016-03-11.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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