Stuart C. Ray
Stuart C. Ray is an American physician. He is Vice Chair of Medicine for Data Integrity and Analytics,[1] Associate Director of the Infectious Diseases Fellowship Training Program at the Johns Hopkins School of Medicine, and a Professor in the Department of Medicine, Division of Infectious Diseases. Ray also holds appointments in Viral Oncology and the Division of Health Sciences Informatics. He is affiliated with the Institute for Computational Medicine[2] at Johns Hopkins and is licensed to practice medicine in Maryland.
Ray researches the influence of
Education and training
As an undergraduate, Ray studied at the California Institute of Technology and graduated from Vanderbilt University with a B.S. cum laude in molecular biology. He remained at Vanderbilt for medical school and received his M.D. in 1990.
Ray completed a
HIV research
Ray has studied the ability of HIV to undergo high levels of mutation in its genomic sequence, exploring the health consequences of this mutability.[4] In 1999, Ray and colleagues reported on the sequence diversity of HIV in India. They cautioned that different subtypes could combine, thwarting traditional efforts to develop vaccines.[5][6]
In 2005, along with colleagues including
Ray has also participated in the study of
HCV research
As HCV evades the immune system, Ray found, its genome not only mutates to escape the body's defenses, but also reverts to its previous, "ancestral" state when possible. This balance helps the virus to retain fitness.[11][12]
Ray's work on HCV has characterized sources of selective pressure on the HCV genome[13] and identified factors leading to HCV immune escape.[14][15]
The interactions between HCV and HIV infections have also been a topic of interest for Ray.[16][17][18][19] He has been interviewed by numerous media outlets, including Newsweek.[20][21][22]
Elected memberships
References
- ^ "Vice Chair for Data Integrity and Analytics announced | Medicine Matters". 8 May 2015.
- ^ ICM affiliated faculty Archived 2012-12-11 at archive.today
- ^ Stuart Ray's CV, JHU ICM website Archived 2010-06-10 at the Wayback Machine
- ^ "HIV's Success Might Lie in Its Mutations," United Press International, November 5, 2002.
- ^ "Sequencing of HIV from India Waves a Red Flag for Vaccine Developers," Gene Therapy Weekly, January 25, 1999.
- PMID 9847317.
- ^ "Small increases or 'blips' in HIV levels do not signal mutations leading to drug-resistant HIV"
- PMID 15073683.
- ^ "Rare Case Explains Why Some Infected with HIV Remain Symptom Free without Antiretroviral Drugs" Newswise, August 12, 2008.
- PMID 18495769.
- ^ "Johns Hopkins Team Finds 'Ancestral' Hepatitis-C Virus at Root of Evolution in Acute and Chronic Infections. AScribe, June 9, 2005.
- PMID 15939791.
- PMID 19303013.
- PMID 18941234.
- PMID 19050238.
- PMID 11238852.
- PMID 19773633.
- PMID 18769357.
- PMID 18457674.
- ^ "Hepatitis C: The Insidious Spread Of A Killer Virus" Newsweek, Geoffrey Cowley, April 22, 2002.
- ^ "The Insidious Spread of a Killer Virus" Newsweek, Anna Kuchment, May 20, 2002.
- ^ "Johns Hopkins Team Finds 'Ancestral' Hepatitis-C Virus At The Root Of Evolution In Infections" ScienceDaily, June 10, 2005.
- ^ Stuart Ray's profile at the American Society for Clinical Investigation