Talk:Levophacetoperane

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I decided to put the structure for the racemic form of phacetoperane on the page, even though PubMed shows the levo isomer. It seems that levophacetoperane is the INN name for the drug, but the references seem to be talking about the racemate and there are no references that I could find which look at the pure levo isomer. Besides, the dextro isomer of methylphenidate seems to be the more active isomer, so I'm not sure why the levo isomer of phacetoperane would be the preferred one, it doesn't seem to make sense. Until there is more information available I shall assume that phacetoperane is used as the racemic mix.Meodipt 01:45, 19 October 2007 (UTC)[reply]

ANSWER: This compound overlays dexmethylphenidate very well - aromatic, amine, ester. I would presume effects are very similar (possibly this is longer acting). — Preceding unsigned comment added by 86.30.243.179 (talk) 11:21, 7 November 2011 (UTC)[reply]

For whatever its worth, the 1972 edition of Psychotropic Drugs and Related Compounds put out by the department of health identifies this as a

Some of the unused isomers are less or not active but one is classed as a depressant. It's my opinion that this is due to opioid activity (look at nortilidine). A propenyl ester might yield a reasonably potent opioid at that. I have failed to find any follow-up information on the other isomers. — Preceding unsigned comment added by 86.30.243.179 (talk) 17:43, 17 September 2011 (UTC)[reply]

Is the reference to 'reversed esters' a good one? It is an awfully big paper to explain a simple concept. — Preceding unsigned comment added by 86.30.243.179 (talk) 17:43, 17 September 2011 (UTC)[reply]