Talk:Ventricular assist device

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Dates and citations

This article clearly shows the need to include dates that are relevant to statements - for instance the paragraph about the oldest surviving patient has been in the article for over a year and cannot still be true - either he has survived longer than the paragraph suggests or he is now dead. Similar comments can be made about other paragraphs which include phrases such as "Recently entered Clinical Trials."

The article also needs a lot more citations than it currently has.

I plead guilty to offences on both counts and will attempt to fix my contributions.

Majurawombat 04:06, 20 June 2007 (UTC)[reply]

I have removed the reference to Gus Rosenberg. The suggestion that his was the first LVAD does not fit with the fact that the LionHeart only entered clinical trials in 2001 whereas the heartmate had completed trials an won FDA approval in 1994. If I am missing something here please say so.

Questions

I thought that studies were indicating that pulseless pumps i.e centrifugal pumps increased hardening of the arteries and other ailments related to high blood pressure. My professor (whom works at the UofL hospital) indicated this during an introductory lecture for heart assist devices.

Dr. Mouth 03:22, 9 November 2006 (UTC)[reply
]

I was under the impression from the liturature that I have reviwed that pulseless pumps did indeed lead to more complications, and that as the human body is designed to work on a pulsed pressure wave that most research is headed in this direction. --LucasRN 06:16, 26 November 2006 (UTC)[reply]

I've tried to find publications comparing pulsatile with non pulsatile LVADS with little success. You probably have access to more literature than I do and should feel free to edit the article with appropriate references. However I would point out that the most recent LVAD to gain CE Mark accreditation (Dec 2006) in Europe is Ventracor's Ventrassist device which is a centrifugal, continuous flow, hydro dynamically suspended pump. Moreover the manufacturers of the two pulsatile implantable devices that are currently approved by the FDA are both working on non pulsatile devices. For instance Thorotec, manufacturers of the HeartMate have gained CE approval(November 2005) for the Heartmate II, a continuous axial flow device which uses two bearings and is working on the HeartMate III a similar device which uses electromagnetic suspension. World Heart maker of the Novacor LVAD has two projects in development. One is an improved pulsatile device the other is a rotary device (centrifugal electomagnetically suspended). World Heart sees these as meeting different types of requirements (pulsatile for end stage patients and non pulsatile for late stage patients).

The third approved implantable device is a rotary continuous flow approved for children.

Both the Hearmate II and the Ventrassist are currently undergoing clinical trials in the US. (Majurawombat 03:29, 29 December 2006 (UTC))[reply]

The patient who has survived the longest with an LVAD has a continuous flow pump.Majurawombat 14:28, 11 September 2007 (UTC)[reply]

I have added a sentence about percutaneous VADs and suggest it can be expanded. Donsmokem (talk) 16:51, 16 March 2008 (UTC)[reply]

AB-180

http://news.bbc.co.uk/1/hi/health/206667.stm 21 year old Julie Mills had an AB-180 implanted for 6 days in 1998 after a virus infected her heart and shut it down. Reader's Digest also ran an article on this pump. I recall it uses hydrodynamic rotor suspension, using water with a small amount of heparin added. http://ats.ctsnetjournals.org/cgi/content/abstract/68/2/768 —Preceding unsigned comment added by Bizzybody (talk • contribs) 09:37, 27 March 2008 (UTC)[reply]

duplicate paragraph

The "retrospective cohort study" paragraph is repeated word for word in both the "REMATCH" and the "Complications and side effects" sections of this article. However, The version in the second mentioned paragraph contains several useful cross-links. I happened to reference this article by chance, and do not have the detailed knowledge to decide positively which should remain, but it seems to me that the links should be transferred to the "REMATCH" paragraph, and the "Complications" & etc.etc., paragraph should be removed. Would this be correct?--Paraballo (talk) 00:57, 13 October 2009 (UTC)[reply]

Citation for Generations

I have found a reference, that discusses the generations and their "meanings" in a scientific paper. It is a review concerning VADs.

All implantable VADs consist of an inflow cannula connecting the left ventricle to the pump that then connects to an outflow cannula carrying augmented blood flow to the aorta.9 These devices are best categorized by their flow characteristics and mechanism used to augment cardiac output via the pump. A volume displacement pump consists of a chamber that passively fills before a pusher plate compresses the chamber and ejects blood in pulsatile fashion through the outflow conduit. Axial flow (or second generation) devices consist of an impellar (a rotor with helical blades) around a central shaft that propels blood by drawing it into the inflow cannula and out through the outflow along the axis of the impellar. Newer centrifugal flow or third-generation pumps have cone-shaped or cylindrical rotors that drive blood flow using the centrifugal force generated from the center of the rotor to its circumference (Fig 1). Contemporary devices such as the HeartMate II (HMII) (Thoratec Corp, Pleasanton, Calif), DuraHeart (Terumo Heart Inc, Ann Arbor, Mich), Jarvik 2000 (Jarvik Heart Inc, New York, NY), and the Heartware left ventricular assist system (LVAS) (Heartware Inc, Miami Lakes, Fla) use the latter 2 mechanisms to generate continuous flow with reduced pulsatility in the systemic circulation. An important limitation to the current technology includes an external driveline in all devices that connects the pump to the controller and battery pack. Despite this limitation, the HMII is approved by the Food and Drug Administration (FDA) for use as a BTT and DT.[1]

--Nightware86 (talk) 16:13, 16 December 2011 (UTC)[reply]

  1. PMID 21875512. {{cite journal}}: |access-date= requires |url= (help); Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help
    )

merge

I suggest merging blood pump into ventricular assist device. As far as I can tell from reading the articles themselves, they are talking about more-or-less the same devices. --DavidCary (talk) 16:29, 26 November 2012 (UTC)[reply]

Though the information for both blood pumps and VADs should be available on either page, the VAD should stay distinct from the blood pump. The blood pump is a larger category of devices that includes LVADs, cardiopulmonary bypass machines, and artificial hearts--all pump blood--which are uniquely different from one another. --Pickelq (talk) 19:30, 9 October 2013

Studies and Outcomes

Suggest some mention of stem cell therapy here as a means of shortening the bridge to recovery.
Mesoblast has been very active in this area, with multiple peer reviewed articles on this, on this page:
http://www.mesoblast.com/science/scientific-publications/cardiac-and-vascular
One reference describes a clinical trial with LVAD with quite impressive results , and some of the other papers are interesting too
Salbayeng (talk) 06:13, 22 February 2016 (UTC)[reply]

Extra devices for list

See http://www.healthcare-in-europe.com/en/article/709.html 81.240.73.229 (talk) 10:11, 6 August 2016 (UTC)[reply]

Hi, that article is 10 years old -- it's even more outdated than this current version of the Wikipedia article is. Softlavender (talk) 23:46, 8 August 2016 (UTC)[reply]
Yes, but some devices weren't in the list. These are:

Please add to article list

Also, are there any devices that have the batteries inside the body as well (similar to pacemakers, ...) see http://www.medscape.com/viewarticle/758065

— Preceding unsigned comment added by 81.240.73.229 (talk) 07:31, 9 August 2016 (UTC)[reply]

  • If you can provide proof (citations) that each of those items are still being manufactured, and proof that they have received CE Mark and/or FDA approval for sale in the EU or US, then we can add them to the chart. Also, the device should be a longterm VAD rather than a short-term (hours or days) device. And the device should be a VAD rather than a TAH or intra-aortic balloon pump. -- Softlavender (talk) 08:24, 9 August 2016 (UTC)[reply]

Ambulatory and community care

doi:10.1161/CIR.0000000000000507 JFW | T@lk 09:40, 21 June 2017 (UTC)[reply]

Wiki Education assignment: WikiProject Medicine Fall 2023 UCF COM

This article was the subject of a Wiki Education Foundation-supported course assignment, between 23 October 2023 and 19 November 2023. Further details are available on the course page. Student editor(s): Tmk1611 (article contribs).

— Assignment last updated by DLEMERGEBM (talk) 21:37, 9 November 2023 (UTC)[reply]


Hello, this is a peer review for the WikiProject Medicine Course with the UCF College of Medicine. Tmk1611 has made a number of updates to this article that have both added article content and citations to support the information. Signifant improvement has been made to the section "Categorization of VADs". In particular the sections about classification of VADs by type of ventricular assistance and duration of assistance have been added and expanded on. There was also some added content regarding potential complications. The new content is written in a style that is both objective and easy to understand, even for a person without a medical background. Additionally, terms used that are unfamiliar to a general audience such as "destination therapy" have been linked to other articles that explain them. Spot checks of the links and citations were all functional. One potential way to improve on the work that was done would be to include some sort of image illustrating what different VADs look like (for example left vs right ventricular devices). Overall good work! — Preceding unsigned comment added by Drall17 (talk • contribs) 20:26, 13 November 2023 (UTC)[reply]

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