Talk:Vidarabine

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The reference "McGuigan, C. Antiviral Chemotherapy – Cardiff University, 3rd Year Pharmacy Notes Lecture Notes." is not a

reliable source and is unverifiable to anyone but McGuigan. Can someone find another references for these statements? --Selket Talk 23:38, 13 March 2007 (UTC)[reply
]


These sentences: "This is where ara-ATP is incorporated into the DNA strand replacing many of the adenosine bases. This results in the prevention of DNA synthesis, as phosphodiester bridges can longer to be built, destabilizing the strand.", especially the last part, is unclear and not very meaningful - if an ara base is incorporated, does that result in the DNA polymerase no longer recognizing the growing strand as a substrate, and therefore lead to strand termination? --Christina Jacobs,
68.80.179.147 (talk) 13:17, 11 August 2008 (UTC)[reply]

More toxic than intravenous Gancyclovir?

Is it really more toxic than Gancyclovir? At the end of the article, it says that side effects are rare and in most cases only occur after high doses. In Gancyclovir, side effects are not so rare. Chaptagai (talk) 22:48, 9 October 2017 (UTC)[reply]