Theodor Boveri

Source: Wikipedia, the free encyclopedia.

Theodor Boveri
Embryonic development
Boveri–Sutton chromosome theory
Centrosome
Chromosome theory of cancer
SpouseMarcella Boveri
ChildrenMargret Boveri
Scientific career
FieldsGenetics, Cell biology

Theodor Heinrich Boveri (12 October 1862 – 15 October 1915) was a German

cytology.[1] He was notable for the first hypothesis regarding cellular processes that cause cancer, and for describing chromatin diminution in nematodes.[2] His brother was industrialist Walter Boveri. Boveri was married to the American biologist Marcella O'Grady (1863–1950).[3] Their daughter Margret Boveri (1900–1975) became one of the best-known journalists in post-World War II Germany.[4]

Work

Using an optical microscope, Boveri examined the processes involved in the fertilization of the animal egg cell; his favorite research objects were the nematode Parascaris and sea urchins.

Boveri's work with

spindle during mitosis in animal cells, which he described as the especial organ of cell division.[6] Boveri also discovered the phenomenon of chromatin diminution during embryonic development of the nematode Parascaris.[8][9]

Building on Carl Rabl's knowledge that chromosomes are also present between two nuclear divisions in the cell nucleus, he developed the concept of chromosome individuality, i.e. the assumption that chromosomes retain their individuality during interphase.[10] Through long experiments on sea urchin eggs, he was also able to prove that the various chromosomes contain different genetic makeup.[11]

He also reasoned in 1902 that a

pathogens.[13][14] His assumption was initially rejected by medical professionals; it was only later that researchers such as Thomas Hunt Morgan in 1915 demonstrated that Boveri was correct.[15][16]

Boveri also described the structure of the kidneys in

Cephalochordata).[17][18]

References

  1. PMID 11619485
    .
  2. PMID 14149391
    .
  3. S2CID 15829893
    .
  4. ^ Baltzer, Fritz (1967). "Theodor Boveri: The Life of a Great Biologist 1862–1915". Archived from the original on 28 February 2005. Retrieved 22 July 2007.. Extract published in Gilbert, SF (2006). DevBio: a companion to Developmental Biology, 8th ed. Sinauer Associates.
  5. PMID 18163986
    .
  6. ^
    S2CID 15479331
    .
  7. ^
    PMID 12226736
    .
  8. PMID 8735909
    .
  9. S2CID 4189392
    .
  10. PMID 20300217
    .
  11. PMID 18163986
    .
  12. ^ Boveri, Theodro (1902). "Über mehrpolige Mitosen als Mittel zur Analyse des Zellkerns". Verh Phys Med Gesellschaft Würzburg. 35: 67–90.
  13. S2CID 9033401
    .
  14. S2CID 29706685
    .
  15. S2CID 12002052
    .
  16. PMID 9237430
    .
  17. PMID 29319116
    .
  18. PMID 29426805
    .

Further reading

External links
Retrieved from "https://en.wikipedia.org/w/index.php?title=Theodor_Boveri&oldid=1219371384"