Urine organic acids

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Urine organic acids
Purposemeasures organic acid metabolites in urine

Urine organic acids is a medical

organic acidemias. It is also used to look for problems with nutrition or evidence of certain infections or bacterial overgrowth. The usual method of analysis is tandem mass spectrometry.[1]


Urine organic acid analysis profile: The 3 prominent peaks on the left are from left to right: B-hydroxybutyrate, Acetoacetate (with TMS derivative 1), Acetoacetate 2nd peak (with TMS derivative 2). TMS = trimethylsilyl derivative reagent, PDA = pentadecanoic acid (internal standard).
GC-MS total ion chromatogram of a urine sample in a patient with diabetic ketoacidosis

References

  1. PMID 20077094
    .


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