User:M2bioinfo-Orsay/sandbox/team8
SQ1002 regulatory sRNA family | |
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Firmicutes | |
PDB structures | PDBe |
SQ1002 regulatory sRNA family
CD630_SQ1002 sRNA
In
SQ002 regulatory sRNA family
General informations
This family is a putative trans-encoded sRNA family. Trans-encoded sRNAs regulate mRNA stability by regulating their level of expression at different locus, the function or mRNA and gene family expression regulated by this family of sRNA is yet unknown. These sRNAs are produced in
Synteny
In term of synteny, all of the Clostridium difficile sRNA gene sequences were in the vicinity of the same family of genes encoding for proteins having an acyl or amino-acyl transfer activity (such as Acyltransferase or Tryptophanyl-tRNA synthetase) and genes encoding for ferrous ions transport proteins, leading to the conclusion that these sRNAs might be independant trans-encoded sRNAs. Moreover, these sRNAs seem to either bind to the positive or negative strand of the mRNAs that need to be regulated during bacterial growth phase since these sRNA seem to be induced at the onset of the Stationnary phase<ref name=OlgaSoutourina>/>. Only the Bacillales species do not have the same family of genes in the vicinity of the sRNA sequence. These sRNA sequences are all located in intergenic regions (repeat region) and are not overlapping any mRNA sequence on any of their UTR.
Références
- doi:10.1093/bioinformatics/btaa080.)
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