WARS2
| WARS2 | |||
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| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
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| UniProt | |||||||||
| RefSeq (mRNA) |
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| RefSeq (protein) |
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| Location (UCSC) | Chr 1: 119.03 – 119.14 Mb | Chr 3: 99.05 – 99.15 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Tryptophanyl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the WARS2 gene.[5][6][7]
Function
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their
autosomal recessive intellectual disability and a syndrome of severe infantile‐onset leukoencephalopathy.[8]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000116874 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000004233 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- S2CID 28931531.
- PMID 10828066.
- ^ a b "Entrez Gene: WARS2 tryptophanyl tRNA synthetase 2, mitochondrial".
- PMID 29120065.
Further reading
- Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. PMID 9373149.
- Liu J, Shue E, Ewalt KL, Schimmel P (2004). "A new gamma-interferon-inducible promoter and splice variants of an anti-angiogenic human tRNA synthetase". Nucleic Acids Research. 32 (2): 719–727. PMID 14757836.
- Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, et al. (December 2005). "Transcriptome analysis of human gastric cancer". Mammalian Genome. 16 (12): 942–954. S2CID 69278.
- Guo LT, Chen XL, Zhao BT, Shi Y, Li W, Xue H, Jin YX (2007). "Human tryptophanyl-tRNA synthetase is switched to a tRNA-dependent mode for tryptophan activation by mutations at V85 and I311". Nucleic Acids Research. 35 (17): 5934–5943. PMID 17726052.
External links
- WARS2 human gene location in the UCSC Genome Browser.
- WARS2 human gene details in the UCSC Genome Browser.
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