User:Mr. Ibrahem/Brompheniramine

Source: Wikipedia, the free encyclopedia.
Mr. Ibrahem/Brompheniramine
Clinical data
Trade namesBromfed, Dimetapp, Bromfenex, and others
AHFS/Drugs.comMonograph
MedlinePlusa682545
Routes of
administration		By mouth
Drug classAntihistamine[1]
Legal status
Legal status
  • AU: S4 / S3 / S2
  • US: Rx-only / OTC
  • Unscheduled,
    OTC[2]
Pharmacokinetic data
MetabolismLiver
Elimination half-life24.9 ± 9.3 hours[3]
Duration of action48 hrs[1]
ExcretionUrine
Identifiers
  • (R/S)-3-(4-Bromophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine
Chemical and physical data
JSmol)
  • Brc1ccc(cc1)C(c2ncccc2)CCN(C)C
  • InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3 checkY
  • Key:ZDIGNSYAACHWNL-UHFFFAOYSA-N checkY
  (verify)

Brompheniramine, sold under the brand name Dimetapp among others,[2] is an antihistamine used for symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.[1] Its use in children under 6 is not recommended.[4] It is taken by mouth.[1] Maximal effects occur around 6 hours and may may last for up to two days.[1]

Common side effects include sleepiness, restlessness, confusion, dry mouth, and blurred vision.

first-generation antihistamine.[1]

Brompheniramine was patented in 1948 and came into medical use in 1955.

generic medication and are relatively inexpensive.[6][7]

References

  1. ^ a b c d e f g h i j k "Brompheniramine Monograph for Professionals". Drugs.com. Archived from the original on 21 January 2021. Retrieved 17 July 2021.
  2. ^ a b "Brompheniramine Uses, Side Effects & Warnings". Drugs.com. Archived from the original on 28 January 2021. Retrieved 25 March 2021.
  3. PMID 6128358
    .
  4. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link
    )
  5. ISBN 9783527607495. Archived
    from the original on 2021-05-12. Retrieved 2020-12-15.
  6. ^ "Brompheniramine / Dextromethorphan / Pseudoephedrine Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 17 May 2020. Retrieved 17 July 2021.
  7. ^ "Compare Dimetapp Prices". GoodRx. Archived from the original on 3 November 2016. Retrieved 25 March 2021.
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