Vitamin A2
Appearance
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Names | |
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IUPAC name
3,4-Didehydroretinol
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Preferred IUPAC name
(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)nona-2,4,6,8-tetraen-1-ol | |
Other names
Retinol 2; 3,4-Dehydroretinol
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Identifiers | |
3D model (
JSmol ) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard
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100.001.116 |
EC Number |
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KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C20H28O | |
Molar mass | 284.443 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Vitamin A2 is a subcategory of vitamin A.[1]
As with all vitamin A forms, A2 can exist as an aldehyde, Dehydroretinal (3,4-dehydroretinal), an alcohol, 3,4-dehydroretinol (vitamin A2 alcohol) or an acid, 3,4-dehydroretinoic acid (vitamin A2 acid). Many cold-blooded vertebrates use the aldehyde for their visual system to obtain a red-shifted sensitive spectrum.[2]
Human skin naturally contains the alcohol form.[3][4] In humans, CYP27C1 converts ordinary A1 (all-trans retinoids) to A2. The enzyme also converts 11-cis-retinal.[2]
Vitamin A2 was first identified by Richard Alan Morton using newly-developed absorption spectroscopy in 1941.[5]