Wikipedia:VideoWiki/Gout
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Definition
Gout is a form of inflammatory arthritis characterized by recurrent attacks of a single red, tender, hot, and swollen joint.[1][2]
Symptoms 1
Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours.
Symptoms 2
It may also result in
Cause 1
Gout is due to persistently elevated levels of uric acid in the blood.[3][2]
Cause 2
This occurs from a combination of diet, other health problems, and genetic factors.[3][2] At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues, resulting in an attack of gout.[3]
Cause 3
Gout occurs more commonly in those who regularly eat meat or seafood, drink beer, or are overweight.[3][5]
Diagnosis
Diagnosis may be confirmed by the presence of crystals in the joint fluid or in a deposit outside the joint.[3] Blood uric acid levels may be normal during an attack.[3]
Treatment
Treatment with
Prevention
Once the acute attack resolves, levels of uric acid can be lowered via lifestyle changes or allopurinol.[3] Taking vitamin C and eating a diet high in low-fat dairy products may be preventive.[7]
Epidemiology 1
Gout affects about 1 to 2% of the Western population at some point in their lives.[3] It has become more common in recent decades.[3]
Epidemiology 2
Older males are most commonly affected.[3]
History
Gout was historically known as "the disease of kings" or "rich man's disease"
References
- PMID 18830092.
- ^ PMID 28549177.
- ^ PMID 19692116.
- PMID 20203467.
- PMID 27452679.
- PMID 27802478.
- ^ "Questions and Answers about Gout". National Institute of Arthritis and Musculoskeletal and Skin Diseases. June 2015. Archived from the original on 15 January 2016. Retrieved 2 February 2016.
- ^ "Rich Man's Disease – definition of Rich Man's Disease in the Medical dictionary". Free Online Medical Dictionary, Thesaurus and Encyclopedia.