The 1942 United States Senate election in South Dakota took place on November 3, 1942. Incumbent Democratic Senator
Franklin Roosevelt's foreign policy and war preparedness. Former Governor Tom Berry, Bulow's chief opponent, drew a contrast between Bulow's isolationism and his support for Roosevelt's policies.[1] In the end, Berry defeated Bulow in a landslide, and advanced to the general election, where he faced Harlan J. Bushfield, the incumbent Republican Governor of South Dakota. As Republicans gained ground nationwide, Bushfield defeated Berry in a landslide to pick up the seat for the Republican Party. Bushfield did not serve his full term, however; shortly before the 1948 U.S. Senate election