ACSBG1
ACSBG1 | |||
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Identifiers | |||
Gene ontology | |||
Molecular function | |||
Cellular component | |||
Biological process | |||
Sources:Amigo / QuickGO |
Ensembl | |||||||||
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UniProt | |||||||||
RefSeq (mRNA) | |||||||||
RefSeq (protein) | |||||||||
Location (UCSC) | Chr 15: 78.17 – 78.25 Mb | Chr 9: 54.51 – 54.57 Mb | |||||||
PubMed search | [3] | [4] |
View/Edit Human | View/Edit Mouse |
Acyl-CoA Synthetase, Bubblegum Family, member 1 (ACSBG1) is an enzyme that in humans is encoded by the ACSBG1 gene.[5][6][7]
The protein encoded by this gene possesses long-chain
synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis.[7] The conversion of long chain fatty acids into long chain acyl-CoAs in mice is catalysed by ACSBG1.[8]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000103740 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032281 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 9734811.
- PMID 10954726.
- ^ a b "Entrez Gene: ACSBG1 acyl-CoA synthetase bubblegum family member 1".
- PMID 11112418.
External links
- Human ACSBG1 genome location and ACSBG1 gene details page in the UCSC Genome Browser.
Further reading
- Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. PMID 8619474.
- Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. PMID 9110174.
- Moriya-Sato A, Hida A, Inagawa-Ogashiwa M, et al. (2001). "Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues". Biochem. Biophys. Res. Commun. 279 (1): 62–8. PMID 11112418.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
- Pei Z, Oey NA, Zuidervaart MM, et al. (2004). "The acyl-CoA synthetase "bubblegum" (lipidosin): further characterization and role in neuronal fatty acid beta-oxidation." J. Biol. Chem. 278 (47): 47070–8. PMID 12975357.
- Fraisl P, Forss-Petter S, Zigman M, Berger J (2004). "Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase". Biochem. J. 377 (Pt 1): 85–93. PMID 14516277.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039.
- Asheuer M, Bieche I, Laurendeau I, et al. (2005). "Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy". Hum. Mol. Genet. 14 (10): 1293–303. PMID 15800013.