Andrew Lumsden (scientist)
Andrew Lumsden Neurobiology | |
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| Institutions | King's College London Guy's Hospital University of California, Berkeley |
| Website | www |
Andrew Gino Lumsden Medical Research Council Centre for Developmental Neurobiology[3][4] at King's College London.[5][6]
Education
Andrew Lumsden attended
PhD
in Developmental Biology at the University of London.
Career and research
Lumsden has held various lectureships at Guy's Hospital Medical School and the United Medical Schools of Guy's and St. Thomas' Hospital before being made a full Professor of the University of London in 1989. He has been an International Scholar of the Howard Hughes Medical Institute (1993–1998) and a Miller Institute visiting professor at the University of California, Berkeley (1994).
Lumsden has served on the Medical Research Council Neurosciences and Mental Health Board and Grants Committee (1992—1998), the
Faculty of 1000.[9]
Andrew Lumsden has co-authored a book entitled The Developing Brain with Michael Brown and Roger Keynes.hindbrain of mammal and bird embryos confirmed the long suggested but never agreed view that this brain region has a rigidly segmented organisation, much like the body plan of insects and worms. To assist his research, he developed the Lumsden BioScissors™.[11][12] Most recently, he has focussed on the developing forebrain, where he discovered signalling properties in a small set of cells that pattern the large surrounding region of the thalamus.
Awards and honours
Lumsden was elected a
EMBO Member in 2008.[citation needed
]
In 2001, he was awarded The Ferrier Lecture and medal by the Royal Society[1][13] and in 2007, the W. Maxwell Cowan Prize[14] for "outstanding contributions in developmental neuroscience".
Lumsden has also been elected Freeman of the Worshipful Company of Clockmakers in 2006, and raised to the Livery in 2016.[2]
Publications
Lumsden's publications[3] include:
- Lumsden AG, Davies AM (1983). "Earliest sensory nerve fibres are guided to peripheral targets by attractants other than nerve growth factor". Nature. 306 (5945): 786–8. S2CID 4317445.
- Lumsden AG, Davies AM (1986). "Chemotropic effect of specific target epithelium in the developing mammalian nervous system". Nature. 323 (6088): 538–9. S2CID 4363988.
- Tessier-Lavigne M, Placzek M, Lumsden AG, Dodd J, Jessell TM (1988). "Chemotropic guidance of developing axons in the mammalian central nervous system". Nature. 336 (6201): 775–8. S2CID 4247407.
- Lumsden A (March 1989). "Multipotent cells in the avian neural crest". Trends Neurosci. 12 (3): 81–3. S2CID 31991456.
- Lumsden A, Keynes R (February 1989). "Segmental patterns of neuronal development in the chick hindbrain". Nature. 337 (6206): 424–8. S2CID 4262186.
- Heffner CD, Lumsden AG, O'Leary DD (January 1990). "Target control of collateral extension and directional axon growth in the mammalian brain". Science. 247 (4939): 217–20. PMID 2294603.
- Fraser S, Keynes R, Lumsden A (March 1990). "Segmentation in the chick embryo hindbrain is defined by cell lineage restrictions". Nature. 344 (6265): 431–5. S2CID 4355552.
- Lumsden A (August 1990). "The cellular basis of segmentation in the developing hindbrain". Trends Neurosci. 13 (8): 329–35. S2CID 3997227.
- Lumsden A, Sprawson N, Graham A (December 1991). "Segmental origin and migration of neural crest cells in the hindbrain region of the chick embryo". Development. 113 (4): 1281–91. PMID 1811942.
- Guthrie S, Muchamore I, Kuroiwa A, Marshall H, Krumlauf R, Lumsden A (March 1992). "Neuroectodermal autonomy of Hox-2.9 expression revealed by rhombomere transpositions". Nature. 356 (6365): 157–9. S2CID 4346647.
- Simon H, Lumsden A (August 1993). "Rhombomere-specific origin of the contralateral vestibulo-acoustic efferent neurons and their migration across the embryonic midline". Neuron. 11 (2): 209–20. S2CID 35121927.
- Lumsden A, Clarke JD, Keynes R, Fraser S (June 1994). "Early phenotypic choices by neuronal precursors, revealed by clonal analysis of the chick embryo hindbrain". Development. 120 (6): 1581–9. PMID 8050364.
- Graham A, Francis-West P, Brickell P, Lumsden A (December 1994). "The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest". Nature. 372 (6507): 684–6. S2CID 4361935.
- Logan C, Wizenmann A, Drescher U, Monschau B, Bonhoeffer F, Lumsden A (1996). "Rostral optic tectum adopts a caudal phenotype following ectopic Engrailed expression". Current Biology. 6 (8): 1006–1014. S2CID 15159391.
- Lumsden A, Krumlauf R (1996). "Patterning the vertebrate neuraxis". Science. 274 (5290): 1109–1115. S2CID 10891464.
- Studer M, Lumsden A, Ariza-McNaughton L, Bradley A, Krumlauf R (1996). "Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1". Nature. 384 (6610): 630–634. S2CID 4317559.
- Bell E, Wingate, R. Lumsden A. (1999). "Homeotic transformation of rhombomere identity following localised Hoxb1 misexpression". Science. 284 (5423): 2168–2171. PMID 10381880.)
{{cite journal}}: CS1 maint: multiple names: authors list (link - Fortin G, Jungbluth S, Lumsden A, Champagnat J (1999). "Segmental specification of GABAergic inhibition during development of hindbrain neural networks" (PDF). Nature Neuroscience. 2 (10): 873–877. S2CID 27168904.
- Zeltser L, Larsen C, Lumsden A (2001). "A new developmental compartment in the forebrain regulated by Lunatic fringe". Nature Neuroscience. 4 (7): 683–684. S2CID 26205097.
- Larsen C, Zeltser L, Lumsden A (2001). "Boundary formation and compartition in the avian diencephalon". Journal of Neuroscience. 21 (13): 4699–4711. PMID 11425897.
- Matsumoto K, Nishihara S, Kamimura M, Shiraishi T, Otoguro T, Uehara M, Maeda Y, Ogura K, Lumsden A, Ogura T (2004). "The prepattern transcription factor Irx2, a target of the FGF8/MAP kinase cascade, is involved in cerebellum formation". Nature Neuroscience. 7 (6): 605–612. S2CID 23807922.
- Kiecker C, Lumsden A (2004). "Hedgehog signalling from the zona limitans intrathalamica regulates the emergence of thalamic and prethalamic identity". Nature Neuroscience. 7 (11): 1242–1249. S2CID 29863625.
- Kiecker C, Lumsden A (2005). "Compartments and their boundaries in vertebrate brain development". Nature Reviews Neuroscience. 6 (7): 553–564. S2CID 10869618.
- Scholpp S, Delogu A, Gilthorpe J, Peukert D, Lumsden A (2009). "Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus". Proceedings of the National Academy of Sciences of the United States of America. 106 (47): 19895–19900. PMID 19903880.
- Scholpp S, Lumsden A (2010). "Building a bridal chamber: development of the thalamus". Trends in Neurosciences. 33 (8): 373–380. PMID 20541814.
- Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A (2012). "Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms". Neuron. 75 (4): 648–662. PMID 22920256.
- Gilthorpe JD, Oozeer F, Nash J, Calvo M, Bennett DL, Lumsden A, Pini A (2013). "Extracellular histone H1 is neurotoxic and drives a pro-inflammatory response in microglia". F1000Research. 2: 148. PMID 24358859.
References
- ^ a b c Anon (1994). "Professor Andrew Lumsden FMedSci FRS". royalsociety.org. Archived from the original on 12 October 2015.
- ^ a b c d e "LUMSDEN, Prof. Andrew Gino". Who's Who. Vol. 2014 (online Oxford University Press ed.). Oxford: A & C Black. (Subscription or UK public library membership required.)
- ^ a b Andrew Lumsden publications indexed by the Scopus bibliographic database. (subscription required)
- ^ "King's College London - Department of Developmental Neurobiology". www.kcl.ac.uk.
- ^ "Lumsden Official Page". Archived from the original on 10 December 2010.
- YouTube
- ^ "Development - The Company of Biologists".
- ^ "Neural Development". Neural Development.
- ^ "Andrew Lumsden: Advisory Board Member in Neurodevelopment: F1000Prime". f1000biology.com. Archived from the original on 1 February 2010.
- ISBN 978-0-19-854793-8.
- ^ "Lumsden Bioscissors™" (PDF). bio-rad.com. Archived from the original (PDF) on 26 July 2011.
- ^ "Obanpi". obanpi.co.uk. Archived from the original on 9 July 2011.
- ^ "Royal Society prize". Archived from the original on 14 April 2003.
- ^ "Cowan and Palay Awards". cajalclub.org. Archived from the original on 25 July 2011.
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