Anosodiaphoria

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Anosodiaphoria
SpecialtyNeurology

Anosodiaphoria is a condition in which a person who has a

neglect syndrome.[1] It might be specifically associated with defective functioning of the frontal lobe of the right hemisphere.[2]

Indifference is different from denial because it implies a lack of caring on the part of the patient, who otherwise acknowledges his or her deficit.[citation needed
]

Signs and symptoms

Causes

A few possible explanations for anosodiaphoria exist:

  1. The patient is aware of the deficit but does not fully comprehend it or its significance for functioning
  2. May be related to an affective communication disorder and defective arousal. These emotional disorders cannot account for the verbal explicit denial of illness of anosognosia.[5]

Other explanations include reduced emotional experience, impaired emotional communication,

behavioral abnormalities, dysexecutive syndrome, and the frontal lobes.[6]

Neurology

Anosodiaphoria occurs after stroke of the brain. 27% of patients with an acute hemispheric stroke had the stroke in the right hemisphere, while 2% have it in their left.[7]

Anosodiaphoria is thought to be related to

unilateral neglect, a condition often found after damage to the non-dominant (usually the right) hemisphere of the cerebral cortex in which patients seem unable to attend to, or sometimes comprehend, anything on a certain side of their body (usually the left).[citation needed
]

The

anterior cingulate-anterior insula area, especially on the right.[8]

Treatment

physical rehabilitation. Patients are not likely to implement rehabilitation for a condition about which they are indifferent. Although anosognosia often resolves in days to weeks after stroke, anosodiaphoria often persists.[9] Therefore, the therapist has to be creative in their rehabilitation approach in order to maintain the interest of the patient.[citation needed
]

See also

References

  1. ^ "Anosodiaphoria." http://cancerweb.ncl.ac.uk/cgi-bin/omd?anosodiaphoria. Online Medical Dictionary[dead link]
  2. .
  3. ^ Prigatano, G. (1991). Awareness of deficit after brain injury: clinical and theoretical issues. New York, New York: Oxford University Press.
  4. ^ Prigatano, G. (2010). The study of anosognosia. New York, New York: Oxford University Press.
  5. .
  6. ^ Prigatano, G. (2010). The study of anosognosia. New York, New York: Oxford University Press.
  7. ^ Stone, S.P. Halligan, P.W., and Greenwood, R.J. (1993). The incidence of neglect phenomenon and related disorders in patients with an acute right or left hemisphere stroke. Age and Aging, 22, 46-52.
  8. ^ Mendez, M.F. & Shapira, J.S. (2011). Loss of emotional insight in behavioral variant frontotemporal dementia or "frontal anosodiaphoria".Consciousness and Cognition, 20(4), 1690-1696.
  9. ^ Barrett, A.M., Buxbaum, L.J., Coslett, H.B., Edwards, E., Heilman, K.M., Hillis, A.E., Milberg, W.P., and Robertson, I.H. (2006). Cognitive rehabilitation interventions for neglect and related disorders: moving from bench to bedside in stroke patients. Journal of Cognitive Neuroscience, 18(7), 1223-1236.