ArrayTrack
U.S. Food and Drug Administration | |
| Stable release | 3.5.0
/ March 3, 2010 |
|---|---|
Mac OS X, Windows | |
| Platform | Java |
| Type | Bioinformatics data management, analysis, and interpretation |
| Website | [1] |
ArrayTrack is a multi-purpose bioinformatics tool primarily used for
Features
ArrayTrack is composed of three major components: Study Database, Tools, and Libraries, which primarily handle data management, analysis, and interpretation, respectively. Each of these components can be directly accessed from the other two, e.g., analysis Tools can be used directly on experimental data stored in the Study Database, and significant genes discovered from the results can be queried in the Libraries to view additional annotations and associated proteins, pathways, Gene Ontology terms, etc.[2]
- Study Database: The Study Database contains user-imported experiment data, including both raw data and annotation data. It is mainly used to manage microarray data, but also supports proteomics and metabolomics data. Imported data are initially private to the owner but can be made available to other users. The Study Database also stores significant gene lists, which can be created directly from data analysis results in ArrayTrack.
- Tools: A wide variety of analysis and visualization Tools are available in ArrayTrack, including but are not limited to: statistical analysis Tools including SAM-Test; unsupervised pattern discovery Tools including Hierarchical Clustering Analysis and Principal Component Analysis; and model prediction Tools including K-Nearest Neighbors and Linear Discriminant Analysis. Although ArrayTrack's Tools are designed to accommodate imported data, they are also compatible with external data.
- Libraries: ArrayTrack hosts a collection of Libraries which store specific annotation data, viewable in a dynamic spreadsheet format. There is a Library specific for QTL, chip types, and more. Each Library supports multi-input searching, sorting, filtering, copy-pasting, and exporting. Libraries can be directly queried for the desired contents of stored gene lists, analysis results, and other Libraries. A specific entry in any Library can be linked to the equivalent entry in many popular public knowledge bases, including the original sources of data.
ArrayTrack is directly integrated with a variety of other bioinformatics software, such as pathway analysis tools GeneGo MetaCore and Ingenuity Pathway Analysis.[3][4]
Accessibility
ArrayTrack is freely available to the public and can be accessed online. It is run on the client's computer using a
References
- PMID 14630514.
- ISBN 978-1-60761-174-5.
- ^ "The U.S. Food and Drug Administration will use GeneGo's Metacore for "omics" research and reviewing of genomics data" (PDF). Retrieved 2011-04-13.
- ^ "The U.S. Food and Drug Administration to use Ingenuity Pathway Analysis in review of Pharmacogenomics Submissions" (PDF). Retrieved 2011-04-13.