CIDEA
Cell death activator CIDE-A is a protein that in humans is encoded by the CIDEA gene.[5][6][7] Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids.[8]
This gene encodes the
isoforms have been identified.[7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000176194 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024526 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 9564035.
- PMID 18509062.
- ^ a b "Entrez Gene: CIDEA cell death-inducing DFFA-like effector a".
- ^ Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids
External links
- Human CIDEA genome location and CIDEA gene details page in the UCSC Genome Browser.
Further reading
- Zhang L, Miyaki K, Nakayama T, Muramatsu M (2008). "Cell death-inducing DNA fragmentation factor alpha-like effector A (CIDEA) gene V115F (G-->T) polymorphism is associated with phenotypes of metabolic syndrome in Japanese men". Metab. Clin. Exp. 57 (4): 502–5. PMID 18328351.
- Li D, Da L, Tang H, et al. (2008). "CpG methylation plays a vital role in determining tissue- and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 binding". Nucleic Acids Res. 36 (1): 330–41. PMID 18033804.
- Gummesson A, Jernås M, Svensson PA, et al. (2008). "Relations of adipose tissue CIDEA gene expression to basal metabolic rate, energy restriction, and obesity: population-based and dietary intervention studies". J. Clin. Endocrinol. Metab. 92 (12): 4759–65. PMID 17895319.
- Iwahana H, Yakymovych I, Dubrovska A, et al. (2007). "Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell death-inducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis". Proteomics. 6 (23): 6168–80. S2CID 86406116.
- Dahlman I, Kaaman M, Jiao H, et al. (2005). "The CIDEA gene V115F polymorphism is associated with obesity in Swedish subjects". Diabetes. 54 (10): 3032–4. PMID 16186410.
- Nordström EA, Rydén M, Backlund EC, et al. (2005). "A human-specific role of cell death-inducing DFFA (DNA fragmentation factor-alpha)-like effector A (CIDEA) in adipocyte lipolysis and obesity". Diabetes. 54 (6): 1726–34. PMID 15919794.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039.
- Zhou Z, Yon Toh S, Chen Z, et al. (2003). "Cidea-deficient mice have lean phenotype and are resistant to obesity". Nat. Genet. 35 (1): 49–56. S2CID 12428229.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
- Chen Z, Guo K, Toh SY, et al. (2000). "Mitochondria localization and dimerization are required for CIDE-B to induce apoptosis". J. Biol. Chem. 275 (30): 22619–22. PMID 10837461.
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