Dihydroquinine
Names | |
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IUPAC name
(R)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
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Other names
(8α,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol
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Identifiers | |
3D model (
JSmol ) |
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ChemSpider | |
ECHA InfoCard
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100.007.578 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C20H26N2O2 | |
Molar mass | 326.440 g·mol−1 |
Melting point | 173–175 °C |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dihydroquinine, also known as hydroquinineSharpless dihydroxylation.
DHQ also inhibits growth of the parasite Toxoplasma gondii by inducing mitochondrial membrane damage, but does not disrupt host mitochondrial membrane potential, as well as reactive oxygen species (ROS) generation.[2]
See also
References
- ^ "Dihydroquinine chemical information". ChemIndustry.com.
- PMC 9131874.