ELP3
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| Location (UCSC) | Chr 8: 28.09 – 28.19 Mb | Chr 14: 65.77 – 65.83 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Elongator complex protein 3, also named KAT9, is a
projection neurons through acetylation of alpha-tubulin in the developing cerebral cortex.[7] In mammals, ELP3 is important for paternal DNA demethylation after fertilization.[8] ELP3 is potentially involved in cellular redox homeostasis by mediating the acetylation of glucose-6-phosphate dehydrogenase.[9] Besides, ELP3 may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4
.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000134014 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022031 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 11714725.
- ^ "Entrez Gene: ELP3 elongation protein 3 homolog (S. cerevisiae)".
- S2CID 18351772.
- PMID 20054296.
- PMID 24769394.
Further reading
- Rengo F, Brevetti G, Piscione F, et al. (1977). "[Behavior of some metabolic parameters during post-ischemic and post-contraction vasodilation in normal subjects]". Bollettino della Società italiana di cardiologia. 20 (12): 1801–6. PMID 10936.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
- Ninomiya Y, Okada M, Kotomura N, et al. (1996). "Genomic organization and isoforms of the mouse ELP gene". J. Biochem. 118 (2): 380–9. PMID 8543574.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. PMID 11256614.
- Kim JH, Lane WS, Reinberg D (2002). "Human Elongator facilitates RNA polymerase II transcription through chromatin". Proc. Natl. Acad. Sci. U.S.A. 99 (3): 1241–6. PMID 11818576.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039.
- Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. S2CID 11683986.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. PMID 15489336.
- Kouskouti A, Talianidis I (2005). "Histone modifications defining active genes persist after transcriptional and mitotic inactivation". EMBO J. 24 (2): 347–57. PMID 15616580.
- Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. S2CID 39457788.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. PMID 16381901.
- Han Q, Hou X, Su D, et al. (2007). "hELP3 subunit of the Elongator complex regulates the transcription of HSP70 gene in human cells". Acta Biochim. Biophys. Sin. (Shanghai). 39 (6): 453–61. PMID 17558451.
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