Elwira Lisowska

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Prof. Elwira Lisowska
Bar of the Order of Polonia Restituta, Knight's Cross

Elwira Lisowska (born May 6, 1930) is a Polish

P1PK blood group systems
, and to the immunochemical characterization of glycopeptide antigens.

Early life and education

Lisowska was born in

blood group antigens.[1] She earned her doctoral degree in 1962, and in the years 1969-1970 she spent one year as a post-dotoral fellow at Massachusetts General Hospital, where she worked with Roger W. Jeanloz.[1]

Research and career

For many years Lisowska worked on the

polypeptide chain. Lisowska was the first to show that there was a difference between the amino acid residues at positions 1 and 5 of M and N antigens.[1][2]

Beyond her work on

P1PK antigen system.[4] and showed that the NOR antigen is recognized by antibodies present in most of human sera.[5] In addition, she showed that carcinoembryonic antigen forms dimers in solution[6] and was the first to demonstrate that human Band 3 anion transport protein is proteolytically degraded during the lifespan of erythrocyte.[7] She characterized several lectins, including Vicia graminea lectin which is specific for human N blood group antigen,[8] described novel methods of lectin modifications[9] and proved that they are valuable tools in glycoconjugate research.[10] She participated in elucidation of structure and function of glycans from human glycophorin A[11][12] and glycophorin C.[13] She obtained and characterized several monoclonal antibodies recognizng M and N blood group antigens,[14] as well as other fragments of glycophorin A.[15] These studies were important in characterization of antigenic properties of human glycophorins.[16]

She became head of Laboratory of Tissue Immunochemistry (later Laboratory of Glycoconjugate Immunochemistry) at the Hirszfeld Institute of Immunology and Experimental Therapy in 1973. In 1980 she became full professor. In the years 1992–2000 she was deputy director of the Hirszfeld Institute of Immunology and Experimental Therapy. She was a promoter of 9 Ph.D. theses. Elwira Lisowska served also as editor of the journal

European Journal of Biochemistry (1979–1987), Glycoconjugate Journal (1984–1990), Acta Biochimica Polonica (1977–2015), and Advances of Clinical and Experimental Medicine (2000–2003).[1] In 2001 Elwira Lisowska retired from the Hirszfeld Institute of Immunology and Experimental Therapy.[1]

Awards and honours

Select publications

References

  1. ^
    S2CID 220483550
    .
  2. PMID 1027437
    .
  3. PMID 15158664
    .
  4. PMID 11504714
    .
  5. PMID 12626386
    .
  6. PMID 6615527
    .
  7. PMID 2455637
    .
  8. PMID 7067692
    .
  9. PMID 7810865
    .
  10. S2CID 31163600
    .
  11. PMID 20434428
    .
  12. PMID 8384526
    .
  13. PMID 25552259
    .
  14. PMID 2443838
    .
  15. PMID 1376415
    .
  16. PMID 14533797
  17. ^ "FEBS | The Polish Biochemical Society | Our Members". www.febs.org. Retrieved 2020-07-16.
  18. ^ "Postanowienie Prezydenta Rzeczypospolitej Polskiej". Nadanie Orderów i Odznaczeń. Retrieved 2020-07-30.
  19. ^ "Diplome d'Honneur of Polish Biochemical Society". Hirszfeld Institute of Immunology and Experimental Therapy Twitter Account (in Polish). 2016-09-21. Retrieved 2020-07-27.
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