Epoxiconazole
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IUPAC name
(2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole
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Identifiers | |
3D model (
JSmol ) |
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ChEBI |
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ChemSpider | |
ECHA InfoCard
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100.100.840 |
KEGG | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C17H13ClFN3O | |
Molar mass | 329.76 g mol |
Density | 1.374 g/cm3 |
Melting point | 134 °C (273 °F; 407 K) |
8.42 ppm, at 20°C in water | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Epoxiconazole is a
Use
Epoxiconazole is used against, amongst others, cereal diseases, two of which, namely leaf blotch (
Resistance
Certain plant pathogens develop
Mode of Action
As an azole, Epoxiconazole, actively stops the production of new fungi spores and inhibits the biosynthesis of existing hostile cells. Epoxiconazole works as an eradicant by encapsulating fungal
Regulation
In Europe, the active substance epoxiconazole has been withdrawn by industry from the approval process under Regulation (EC) No 1107/2009. The effect of that withdrawal is that epoxiconazole is banned from all use in the category ‘pesticides’, due to the fact that it has not been approved for any other use in that category.
In addition, the harmonised classification of epoxiconazole under Regulation (EC) No 1272/2008 of the European Parliament and of the Council [9] is sufficient evidence that the substance raises concerns for human health and the environment.
According to the
References
- ^ https://www3.epa.gov/pesticides/chem_search/reg_actions/registration/fs_PC-123909_01-Aug-06.pdf [bare URL PDF]
- ^ Wikimedia Epoxiconazole
- ^ Zhang XY, Loyce C, Meynard JM, Savary S: Characterization of multiple disease systems and cultivar susceptibilities for the analysis of yield losses in winter wheat. In: Crop Protection. Nr. 25, 2006, pg. 1013-1023.
- S2CID 135799368.
- ^ "New Challenges for Triazoles. Farmers Journal, Crop Protection" (PDF). McCabe T. 2004. Archived from the original (PDF) on 2011-07-22.
- ^ "Research and Development, Annual Project Report. Project number: RD-2004-3025. Fungicide performance network. Up to date information on fungicide performance for wheat growers". HGCA (Home Grown Cereals Authority). 2007. Archived from the original on 2007-06-06.
- ^ "The wheat disease management guide". HGCA (Home Grown Cereals Authority) McCabe T. 2010. Archived from the original on 2011-07-11.
- ^ Xu X, Nicholson P and Ritieni A.: Effects of fungal interactions among Fusarium head blight pathogens on disease development and mycotoxin accumulation. In: International Journal of Food Microbiology Nr. 119 (1-2), 2007, pg. 67-71.
- ^ "Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006". 2008-12-31.
- ^ "ECHA Epoxiconazole Substance Infocard".