Frank Uhlmann
Frank Uhlmann | |
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 Frank Uhlmann in 2015, portrait via the Royal Society | |
| Alma mater | University of Tübingen (PhD) |
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| Thesis | Reconstitution and characterisation of human replication factor C (1997) |
| Website | crick |
Frank Uhlmann FRS[1] is a group leader at the Francis Crick Institute in London.[6][7][8][9][10][11][12]
Education
Uhlmann was educated at the University of Tübingen where he was awarded a PhD in 1997.[4][13] During his PhD, he worked with Jerard Hurwitz at the Memorial Sloan Kettering Cancer Center in New York City.[14][15][16]
Career
Following his PhD, Uhlmann moved to the
postdoctoral research with Kim Nasmyth. In 2000, he established a laboratory at the Imperial Cancer Research Fund (now Cancer Research UK)[17] in London, which ultimately became part of the Francis Crick Institute.[16]
Awards and honours
Uhlmann was elected a
transcription distinct from the sites where their loading factors bind, apparently reflecting interaction with the transcription apparatus; and that cohesin loading factors are recruited to specific chromosomal sites through interaction with the nucleosome remodelling complex Rsc. He has identified genes required for cohesion establishment, and shown that one of these, EcoI, acetylates cohesin during DNA replication, thereby locking it onto DNA and his studies of the link between cohesion regulation and the cell cycle have shown that as well as cleaving cohesin, separase promotes mitotic exit by activating the Cdc14 phosphatase in a protease-independent manner.[1]
In 2006, Uhlmann was also elected a member of the European Molecular Biology Organization (EMBO)[2] and awarded the EMBO Gold Medal.[5][3]
References
- ^ a b c "Dr Frank Uhlmann FRS: Group Leader, The Francis Crick Institute". London: The Royal Society. Archived from the original on 2 May 2015.
- ^ a b "The EMBO Pocket Directory" (PDF). European Molecular Biology Organization. Archived from the original on 16 March 2015.
- ^ PMID 17962808.
- ^ a b "Frank Uhlmann: Mechanism and control of chromosome segregation". The Crick Institute. Archived from the original on 24 May 2015.
- ^ a b "Frank Uhlmann of London Research Institute wins 'EMBO Gold'". EMBO. Archived from the original on 14 April 2015.
- ^ Frank Uhlmann's publications indexed by the Scopus bibliographic database. (subscription required)
- S2CID 4354549.
- S2CID 2667617.
- PMID 9990856.
- PMID 10827941.
- PMID 25569132.
- PMID 25922992.
- OCLC 51443586.
- PMID 9092550.
- PMID 8692848.
- ^ a b "Frank Uhlmann biography". London: Francis Crick Institute. Archived from the original on 25 May 2015.
- ^ "Frank Uhlmann: Understanding how cells divide". Cancer Research UK. Archived from the original on 27 May 2015.
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