IGF2BP2
| IGF2BP2 | |||
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| Location (UCSC) | Chr 3: 185.64 – 185.83 Mb | Chr 16: 21.88 – 21.98 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Insulin-like growth factor 2 mRNA-binding protein 2 is a protein that in humans is encoded by the IGF2BP2 gene.[5][6][7]
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four
5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[7]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000073792 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033581 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 10190901.
- PMID 9891060.
- ^ a b "Entrez Gene: IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2".
Further reading
- Yisraeli JK (2005). "VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins". Biol. Cell. 97 (1): 87–96. S2CID 8767105.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
- Moraes KC, Quaresma AJ, Maehnss K, Kobarg J (2003). "Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D)". Biol. Chem. 384 (1): 25–37. S2CID 30993043.
- Brants JR, Ayoubi TA, Chada K, et al. (2004). "Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2". FEBS Lett. 569 (1–3): 277–83. S2CID 31167314.
- Ping S, Wang S, Zhang J, Peng X (2005). "Effect of all-trans-retinoic acid on mRNA binding protein p62 in human gastric cancer cells". Int. J. Biochem. Cell Biol. 37 (3): 616–27. PMID 15618018.
- Hammer NA, Hansen TO, Byskov AG, et al. (2005). "Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer". Reproduction. 130 (2): 203–12. PMID 16049158.
- Natkunam Y, Vainer G, Chen J, et al. (2007). "Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms". Haematologica. 92 (2): 176–83. PMID 17296566.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. PMID 17353931.
- Cleynen I, Brants JR, Peeters K, et al. (2007). "HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB". Mol. Cancer Res. 5 (4): 363–72. S2CID 21026667.
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