Ilaprazole

Source: Wikipedia, the free encyclopedia.
Ilaprazole
Clinical data
Trade namesNoltec
Routes of
administration		Oral
ATC code
  • None
Identifiers
  • 2-[(RS)-[(4-methoxy-3-methylpyridin-2-yl)methyl]sulfinyl]-5-(1H-pyrrol-1-yl)-1H-benzimidazole
JSmol)
  • Cc1c(OC)ccnc1CS(=O)c2[nH]c3ccc(cc3n2)n4cccc4
  • InChI=1S/C19H18N4O2S/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23/h3-11H,12H2,1-2H3,(H,21,22)
  • Key:HRRXCXABAPSOCP-UHFFFAOYSA-N

Ilaprazole (trade name Noltec) is a

duodenal ulcer.[2][3]

It is available in strengths of 5, 10, and 20 mg.

Clinical studies show that ilaprazole is at least as potent a PPI as

reflux oesophagitis
.

Ilaprazole is developed by Il-Yang Pharmaceutical (Korea), and is still under clinical trials with US FDA. It has launched in Korea and China for the treatment of gastric ulcer, duodenal ulcer, gastroesophageal reflux disease and erosive esophagitis.[4]

Ilaprazole is sold in Mexico by Chinoin Pharmaceuticals under the brand name Norutec.[5]

References

  1. S2CID 38638311
    .
  2. PMID 24377157
    .
  3. PMID 24803828
    .
  4. ^ Clinical trial number NCT00952978 for "Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients (Phase 3)" at ClinicalTrials.gov
  5. ^ "Norutec". Chinoin Pharmaceuticals.
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