Lacto-2 RNA motif
The lacto-2 RNA motif is an
Lactobacillales.[1] The motif consists of a stem-loop whose stem is interrupted by many internal loops and bulges. Nucleotide
identities in many places are conserved, and one internal loop in particular is highly conserved.
As lacto-2 RNAs are not consistently located in
rRNAs, and many are adjacent to genes encoding protein subunits of the ribosome, although they are not necessarily in the same operon as these protein-coding genes. Lacto-2 RNAs also have a weak association with genes involved in nucleotide biosynthesis and transport, including several independent genes within the de-novo purine biosynthesis pathway and some in pyrimidine
biosynthesis.
References
- PMID 17621584.