Leo Loeb

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Leo Loeb
University of Illinois at Chicago, University of Pennsylvania

Leo Loeb (September 21, 1869 – December 28, 1959), was a German-American

pathologist
.

Early life

Loeb, son of a Jewish family from the German

physiologist, led Loeb to decide to pursue a career in experimental medicine.[1]

His brother had a teaching position at the

malignant cells. As an outgrowth of the latter topic, Loeb developed the cell culture technique as applied to both normal and abnormal tissues.[3]

Loeb was next asked to join the faculty at

hereditary,[3] as it is now known to be in some human cases.[4]

Loeb was elected to the American Philosophical Society in 1910.[5]

Career at Washington University

By 1910, Loeb had acquired a national reputation for his work on cancer.

ovaries.[6] That work predated clinical application of the same concept in human breast cancer by several decades.[7]

In 1915, Loeb was appointed as professor of comparative pathology at

endocrine disease. Loeb was known as a patient, kind, and helpful mentor to younger colleagues in the department.[1] He was elected to the United States National Academy of Sciences in 1937.[8]

Retirement and death

Loeb retired from doing active research in 1941, at the age of 72. From then on, he concentrated on the meaning of his findings in an increasingly existential context.[9] This train of thought was reflected in another publication, in 1945, of a book entitled The Biological Basis of Individuality.[10] Loeb proposed three levels of human thought-- "hypnosuggestion;" "reasoning thought;" and "thoughts and interests represented by problems of philosophy and science."

Loeb and his wife remained in St. Louis until his death at the age of 90 in 1959.[4]

References

  1. ^ a b c d e f P. G. Anderson. "Leo Loeb, 1869–1959". Retrieved 1 September 2009.
  2. ^ Suntzeff V: Obituary-- Leo Loeb, 1869-1959. Cancer Res 1960; 20: 972-973.
  3. ^ a b c Goodpasture EW: Leo Loeb, 1869-1959: a biographic memoir. Natl Acad Sci USA, Washington, D.C., 1961.
  4. ^ a b c Kenemans P, Verstraeten RA, Verheijen RH. Oncogenic pathways in hereditary and sporadic breast cancer. Maturitas 2008; 61: 141-150.
  5. ^ "APS Member History". search.amphilsoc.org. Retrieved 2023-12-04.
  6. PMID 21061734
    .
  7. ^ Galante M, McCorkle HJ: Clinical evaluation of bilateral adrenalectomy and oophorectomy for advanced mammary carcinoma. Am J Surg 1955; 90: 180-188.
  8. ^ "Leo Loeb". www.nasonline.org. Retrieved 2023-12-04.
  9. ^ Loeb L: Autobiographical notes. Perspect Biol Med 1958; 2: 1-23.
  10. ^ Loeb L: The Biological Basis of Individuality, C.C. Thomas, Springfield, IL, 1945.

External links