Mendelian traits in humans
(Redirected from
List of Mendelian traits in humans
)
Mendelian traits in humans are human
codominance, and contributions from many genes. If a trait is genetically influenced, but not well characterized by Mendelian inheritance, it is non-Mendelian
.
Examples
- Albinism (recessive)[2]: 53
- Achondroplasia[2]: 53
- Alkaptonuria[2]: 53, 263
- Ataxia telangiectasia[2]: 53
- Brachydactyly (shortness of fingers and toes)[2]: 53
- Colour blindness[2]: 53 (monochromatism, dichromatism, anomalous trichromatism, tritanopia, deuteranopia, protanopia)
- Duchenne muscular dystrophy[2]: 53
- Ectrodactyly[3]
- Ehlers–Danlos syndrome[2]: 53
- Fabry disease[citation needed]
- Galactosemia[2]: 53
- Gaucher's disease[citation needed]
- Some forms of Haemophilia[2]: 53
- Hereditary breast–ovarian cancer syndrome[citation needed]
- Hereditary nonpolyposis colorectal cancer[citation needed]
- HFE hereditary haemochromatosis
- Huntington's disease[2]: 53
- Hypercholesterolemia[2]: 53
- Krabbe disease[citation needed]
- Lactase persistence (dominant) [4]
- Leber's hereditary optic neuropathy[citation needed]
- Lesch–Nyhan syndrome[2]: 53
- Marfan syndrome[2]: 53
- Niemann–Pick disease[citation needed]
- Phenylketonuria[2]: 53
- Porphyria[2]: 53
- Retinoblastoma[citation needed]
- Sickle-cell disease[2]: 53
- Sanfilippo syndrome[citation needed]
- Tay–Sachs disease[2]: 53
- Wet (dominant) or dry (recessive) earwax[5]
Non-Mendelian traits
Most traits (including all complex traits) are non-mendelian. Some traits commonly thought of as Mendelian are not, including:
References
- ^ a b "Inheritance of Sickle Cell Anaemia". Sickle Cell Society. 13 July 2014. Archived from the original on 2018-03-27. Retrieved 2015-12-29.
- ^ ISBN 978-0-321-80311-5.
- PMID 24163146.
- bioRxiv 10.1101/2020.04.23.057356.
- ^ McDonald JH (16 September 2013). "Earwax". Myths of Human Genetics. Baltimore: Sparky House Publishing.
- ^ "Non-Mendelian Genetics". Untamed Science. Retrieved 2018-12-10.
Further reading
- Mange EJ, Mange AR (1999). Basic Human Genetics (second ed.). Sunderland (MA): Sinauer. ISBN 978-0-87893-497-3.
- Simpson SA (November 1999). "Basic Human Genetics". Heredity (Review). 83 (5) (2nd ed.): 635. .
- Speicher MR, Antonarakis SE, Motulsky AG, eds. (2010). Vogel and Motulsky's Human Genetics: Problems and Approaches. Heidelberg: Springer Scientific. S2CID 89318627.