Mycoplasma hyopneumoniae

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Mycoplasma hyopneumoniae
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Mycoplasmatota
Class: Mollicutes
Order: Mycoplasmatales
Family: Mycoplasmataceae
Genus: Mycoplasma
Species:
M. hyopneumoniae
Binomial name
Mycoplasma hyopneumoniae
Maré and Switzer, 1965.[1]

Mycoplasma hyopneumoniae is a species of bacteria known to cause the disease porcine enzootic pneumonia, a highly contagious and chronic disease affecting pigs.[2] As with other mollicutes, M. hyopneumoniae is small in size (400–1200 nm), has a small genome (893–920 kilo-base pairs (kb)) and lacks a cell wall.[3] It is difficult to grow in laboratories due to its complex nutritional requirements and the high chances of contamination associated with mycoplasma culture. To successfully grow the bacterium, an environment of 5–10% carbon dioxide is required, and the medium should demonstrate an acid colour shift.[citation needed]

This bacterium is a concern in the livestock industry as it causes a significant reduction in the growing weight of pigs. Losses in the U.S. have been previously estimated at 200 million to 1 billion dollars per annum.

Vaccines have been found to reduce the severity of the disease but do not prevent the disease from occurring in infected pigs.[6]

Pathogenesis

Mycoplasma hyopneumoniae attaches to the

lesions found in the lungs of pigs with porcine enzootic pneumonia. This damage impedes normal ciliary clearance and often secondary infections develop. On a cellular level, mononuclear infiltration of peribronchiolar and perivascular areas occurs.[citation needed
]

The immune response to M. hyopneumoniae in pigs is slow and ineffective;[5] it is also believed to cause much of the damage that is seen in pigs with the disease.[citation needed] This mycoplasma is not known to produce any specifically harmful toxin like many other disease-causing bacteria, but some mildly toxic by-products have been observed.[7]

Conclusions

Mycoplasma hyopneumoniae has been a topic of interest in the scientific community due to the economic impact of porcine enzootic pneumonia. Three separate

]

References

  1. .
  2. ^ Whittlestone, P. 1979. Porcine Mycoplasmas, p. 133–166. In J. G. Tully and R. F. Whitcomb (ed.), The Mycoplasmas, vol. II. Academic Press, Inc., New York.
  3. PMID 7129633
    .
  4. ^ Clark, LK; Armstrong, CH; Freeman, MJ; Scheidt, AB; Sands-Freeman, L; Knox, K (1991). "Investigating the transmission of Mycoplasma hyopneumoniae in a swine herd with enzootic pneumonia". Veterinary Medicine (USA). 86: 543–50.
  5. ^
    PMID 12045010
    .
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  9. .

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