N,N-Dimethylphenethylamine
Names | |
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Preferred IUPAC name
N,N-Dimethyl-2-phenylethan-1-amine | |
Other names
N,N-Dimethyl-2-phenylethanamine
N,N-Dimethyl-β-phenylethylamine N,N-DMPEA | |
Identifiers | |
3D model (
JSmol ) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard
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100.156.869 |
EC Number |
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PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C10H15N | |
Molar mass | 149.237 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N,N-Dimethylphenethylamine (N,N-DMPEA) is a
flavoring agent. It is an alkaloid that was first isolated from the orchid Eria jarensis.[1] Its aroma is described as "sweet, fishy". It is mainly used in cereal, cheese, dairy products, fish, fruit and meat.[2] It is also being used in pre-workout and bodybuilding supplements with claims of a stimulant effect.[3]
There is also evidence suggesting that N,N-DMPEA acts as a TAAR1 agonist in humans,[4] and as a 5-HT1A ligand in rats. Some less conclusive research also indicated that it had interaction with MAO-B, most likely as an enzyme substrate and not an inhibitor.[5]
N,N-DMPEA is a
positional isomer of methamphetamine. Instead of the methyl group attached to the alpha position of phenylethylamine, it's attached to the nitrogen group. Both substances have the chemical formula C10H15N
.
Safety
N,N-DMPEA has been found to be safe for use as a flavoring agent by the
Food and Agricultural Organization of the United Nations (FAO) and the World Health Organization.[8]
Legality
In the United States, N,N-DMPEA may be considered a Schedule II substance as a positional
defined as "any quantity of methamphetamine, including its salts, isomers, and salts of isomers"[9][10][11]
References
- .
- ISBN 9781420090864. Retrieved 2016-09-13.
- ^ "Eria Jarensis Extract / N-phenethyl dimethylamine: The Next Big Thing?". blog.priceplow.com. Retrieved 2016-10-05.
- S2CID 10829497.
- ^ Pubchem. "N,N-Dimethylphenethylamine | C10H15N - PubChem". pubchem.ncbi.nlm.nih.gov. Retrieved 2016-10-05.
- ^ "Flavor and Extract Manufacturers Association (FEMA) GRAS Flavoring Substances 22". www.femaflavor.org. Retrieved 2019-01-14.
- ^ "Evaluations of the Joint FAO/WHO Expert Committee on Food Additives (JECFA)". apps.who.int. Retrieved 2019-01-14.
- ^ "The Joint FAO/WHO Expert Committee on Food Additives (JECFA)". www.fao.org. Retrieved 2019-01-14.
The Joint FAO/WHO Expert Committee on Food Additives (JECFA) is an international expert scientific committee that is administered jointly by the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO).
- ^ http://isomerdesign.com/Cdsa/FR/36FR12734.pdf [bare URL PDF]
- ^ "21 U.S. Code § 812 - Schedules of controlled substances".
- ^ https://www.govinfo.gov/content/pkg/STATUTE-84/pdf/STATUTE-84-Pg1236.pdf [bare URL PDF]