Oscar Ratnoff
Oscar D. Ratnoff | |
---|---|
Born | |
Died | May 20, 2008 | (aged 91)
Education | Columbia University |
Known for | Discovery of factor XII |
Awards | Kovalenko Medal |
Scientific career | |
Fields | Hematology |
Institutions | Johns Hopkins School of Medicine; Case Western Reserve University School of Medicine |
Oscar Davis Ratnoff (August 23, 1916 – May 20, 2008) was an American physician who conducted research on the process of
Ratnoff was a professor at the Case Western Reserve University School of Medicine, served as president of the American Society of Hematology, and was elected to the National Academy of Sciences. He remained active in research at Case Western Reserve until he was 85 and he died in Cleveland a few years later.
Early life
Ratnoff was born prematurely, the son of a New York pediatrician. Ratnoff's father was an associate of notable pediatrician Henry Koplik. Koplik advised Ratnoff's father that the newborn had little chance of survival and that he should allow the child to die. Instead, Ratnoff's father used hot water bottles to keep him warm. Ratnoff survived and became a strong student at the Brooklyn Boys' School before enrolling at Columbia University when he was 16.[1]
After graduating from Columbia, a 19-year-old Ratnoff entered the
Career
Returning from the military in 1946, Ratnoff secured a fellowship at Johns Hopkins. He became an instructor in medicine there, leaving in 1950 to move to Cleveland. Arthur Patek, the physician who recruited Ratnoff, may have also inspired some interest in coagulation. While a professor at Columbia, Patek had asked Ratnoff to review a research report on cirrhosis from noted physician Ernest Goodpasture. Ratnoff became interested in the observation that the blood of such patients clotted after death but soon turned back to liquid.[1]
While practicing in Cleveland in 1954, Ratnoff treated a young railway worker John Hageman. The man had a long
At Case Western University, Ratnoff was a professor, division chief of hematology-oncology and interim chief of medicine. Ratnoff had a long association with immunologist Irwin Lepow, and they conducted some of the early research on inhibition of the
In the 1980s, Ratnoff became concerned about the risk of
Honors and awards
Ratnoff was the second recipient of the H. P. Smith Award for Distinguished Pathology Educator from the
Later life
Ratnoff, who received his first National Institutes of Health (NIH) research grant in 1951, was still NIH-funded as an emeritus professor in the 1990s.[14] He remained engaged in research at Case Western Reserve until 2001. He died in 2008 and was survived by Marian, his wife of 63 years, and by two children.[8] A sister, Helen Ratnoff Plotz, preceded him in death. She compiled and edited anthologies of poetry.[15]
References
- ^ PMC 2443583.
- ^ "In Memoriam". P&S Journal. Winter 2009.
- PMID 20456750.
- ^ Schmaier, Alvin H.; Gerson, Stanton L. (July 1, 2008). "Oscar D. Ratnoff, MD (1916–2008)". The Hematologist.
- ^ .
- ^ "Henry M. Stratton Medal Recipients (Formerly Lecture)". American Society of Hematology. Retrieved November 12, 2015.
- ^ "Past Presidents". American Society of Hematology. Retrieved November 12, 2015.
- ^ a b Pearce, Jeremy (June 6, 2008). "Oscar Ratnoff, 91, expert on blood clots, is dead". The New York Times.
- ^ "ASCP H. P. Smith Award for Distinguished Pathology Educator". American Society for Clinical Pathology. Retrieved November 12, 2015.
- ^ "Oscar Ratnoff". National Academy of Sciences. Retrieved November 12, 2015.
- ^ "American College of Physicians Masters 1923–Present" (PDF). American College of Physicians. Retrieved November 12, 2015.
- ^ "John Phillips Memorial Award" (PDF). American College of Physicians. Retrieved November 12, 2015.
- ^ "George M. Kober Medal and Lectureship". Association of American Physicians. Retrieved November 11, 2015.
- ^ Huler, Scott (May 25, 1992). "Hanging on to a research grant for decades: What's the secret?". The Scientist.
- ^ "Helen R. Plotz, 87, poetry director". The New York Times. April 10, 2000.