Phosphocholine

Source: Wikipedia, the free encyclopedia.
Not to be confused with phosphatidylcholine.
Phosphocholine
Skeletal formula
Ball-and-stick model
Names
Other names
Choline phosphate
Identifiers
3D model (
JSmol
)
ChemSpider
MeSH Phosphocholine
UNII
  • InChI=1S/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9) ☒N
    Key: YHHSONZFOIEMCP-UHFFFAOYSA-N ☒N
  • InChI=1/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9)
    Key: YHHSONZFOIEMCP-UHFFFAOYAD
  • C[N+](C)(C)CCOP(=O)(O)[O-]
Properties
C5H15NO4P
Molar mass 184.151 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Phosphocholine is an intermediate in the synthesis of phosphatidylcholine in tissues. Phosphocholine is made in a reaction, catalyzed by choline kinase, that converts ATP and choline into phosphocholine and ADP. Phosphocholine is a molecule found, for example, in lecithin.

In

posttranslational modification to suppress an immune response by their hosts.[1][2]

It is also one of the binding targets of C-reactive protein (CRP).[3] Thus, when a cell is damaged, CRP binds to phosphocholine, beginning the recognition and phagocytotic immunologic response.

Phosphocholine is a natural constituent of hens' eggs (and many other eggs) often used in biomimetic membrane studies.[4][5]

See also

  • Alkylphosphocholines
  • Choline
  • Phosphoethanolamine

References

  1. PMID 17766644
    .
  2. ^ "Placenta 'fools body's defences'". BBC News. 2007-11-10. Retrieved 2010-05-22.
  3. PMID 10368284
    .
  4. PMID 16875886
    .
  5. PMID 26301341
    .

External links
Retrieved from "https://en.wikipedia.org/w/index.php?title=Phosphocholine&oldid=1179855255"