Pirbuterol
Clinical data | |
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Trade names | Maxair |
AHFS/Drugs.com | Consumer Drug Information |
MedlinePlus | a601096 |
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Routes of administration | Inhalational (MDI) |
ATC code | |
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Identifiers | |
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JSmol) | |
Chirality | Racemic mixture |
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Pirbuterol (trade name Maxair) is a short-acting β2 adrenoreceptor agonist with bronchodilating action used in the treatment of asthma, available (as pirbuterol acetate) as a breath-activated metered-dose inhaler.
It was patented in 1971 and came into medical use in 1983.[1]
Medical use
Pirbuterol is used in asthma for reversal of acute bronchospasm, and also as a maintenance medication to prevent future attacks. It should be used in patients 12 years of age and older with or without concurrent theophylline and/or inhaled corticosteroid.[2][3]
Mode of action
Pharmacokinetics
After inhalation of doses up to 800
catechol-O-methyltransferase. The plasma half-life measured after oral administration is about two hours.[2]
Adverse effects
References
- ISBN 9783527607495.
- ^ a b "Maxair Autohaler (pirbuterol acetate inhalation aerosol) For Oral Inhalation Only. U.S. Full Prescribing Information". 3M Pharmaceuticals. Northridge, CA 91324. Archived from the original on 20 September 2018. Retrieved 7 March 2016.
- S2CID 21834280.