Sodium butyrate

Source: Wikipedia, the free encyclopedia.
Sodium butyrate
Names
Preferred IUPAC name
Sodium butanoate
Other names
Sodium butyrate
Identifiers
3D model (
JSmol
)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard
 100.005.326 Edit this at Wikidata
UNII
  • InChI=1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
  • CCCC(=O)[O-].[Na+]
Properties
C4H7NaO2
Molar mass 110.088 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Sodium butyrate is a

HDAC activity is estimated to affect the expression of only 2% of mammalian genes.[3]

In the lab, sodium butyrate is usually found as a white, water-soluble, crystalline solid. The chemical is notable for having a very strong, unpleasant smell that lingers.[4] When working with sodium butyrate, gloves, eye protection and respiratory masks are advised for safety purposes.[5]

The compound is found in human diet, notably produced in large amounts from

legumes.[7]

See also

References

  1. S2CID 24214720
    .
  2. S2CID 33206068
    .
  3. PMID 12840228
    .
  4. ^ "Sodium butanoate | 156-54-7". Chemicalbook.com. Retrieved 2016-05-31.
  5. ^ "Sodium butyrate ≥98.5% (GC) | Sigma-Aldrich". Sigmaaldrich.com. Retrieved 2016-05-31.
  6. PMID 22338096
    . Retrieved 27 November 2021 – via diabetes.diabetesjournals.org.
  7. ^ Buettner, Dan (22 May 2015). "Want Great Longevity and Health? It Takes a Village". Wsj.com. Retrieved 27 November 2021.

Further reading

  • Govindarajan, Nambirajan; Agis-Balboa, Roberto Carlos; Walter, Jonas; Sananbenesi, Farahnaz; Fischer, André (2011). "Sodium Butyrate Improves Memory Function in an Alzheimer's Disease Mouse Model When Administered at an Advanced Stage of Disease Progression". Journal of Alzheimer's Disease. 26 (1): 187–97.
    PMID 21593570
    .
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