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There is a page named "Sphingosine kinase" on Wikipedia
Sphingosine kinase (SphK) is a conserved lipid kinase that catalyzes formation sphingosine-1-phosphate (S1P) from the precursor sphingolipid sphingosine...6 KB (627 words) - 09:37, 14 December 2023- important phospholipid. Sphingosine can be phosphorylated in vivo via two kinases, sphingosine kinase type 1 and sphingosine kinase type 2. This leads to...4 KB (219 words) - 13:26, 11 May 2024
coordinated for this purpose. Sphingosine kinase (SK) is a lipid kinase that catalyzes the conversion of sphingosine to sphingosine-1-phosphate (S1P). Sphingolipids...33 KB (3,805 words) - 11:22, 1 April 2024- Sphingosine kinase 2)Sphingosine kinase 2 is a protein that in humans is encoded by the SPHK2 gene. This gene encodes one of two sphingosine kinase isozymes that catalyze the...6 KB (715 words) - 16:10, 19 March 2024
Sphingosine kinase 1 is an enzyme that in humans is encoded by the SPHK1 gene. Sphingosine kinase 1 phosphorylates sphingosine to sphingosine-1-phosphate...10 KB (1,155 words) - 23:34, 8 March 2024
Lipid signaling (section Sphingosine)the formation of sphingosine, Moreover, a phosphate group can be attached to ceramide (phosphorylation) by the enzyme, ceramide kinase. It is also possible...55 KB (5,639 words) - 02:32, 22 June 2024
structural analogue of sphingosine and is phosphorylated by sphingosine kinases in the cell (most importantly sphingosine kinase 2). The molecular biology...27 KB (2,539 words) - 05:53, 26 March 2024
and becomes active when being phosphorylated by kinases. Then the phosphorylated drug binds to sphingosine receptors: not only S1P1, but also S1P3, S1P4...14 KB (1,581 words) - 16:44, 1 February 2024
sphingoid bases, which are a set of aliphatic amino alcohols that includes sphingosine. They were discovered in brain extracts in the 1870s and were named after...24 KB (2,693 words) - 23:05, 9 June 2024
Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid joined by an amide bond. Ceramides are found in high...29 KB (3,310 words) - 03:20, 2 February 2024 - lipid, recruiting cytosolic proteins to appropriate membranes (e.g., sphingosine kinase 1). PA plays very important role in phototransduction in Drosophila...25 KB (3,086 words) - 00:31, 3 December 2023
that is used for the treatment of ulcerative colitis. It is a selective sphingosine-1-phosphate (S1P) receptor modulator that modifies the activity of the...11 KB (698 words) - 05:52, 10 June 2024- acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P). Ceramide...3 KB (328 words) - 13:29, 26 August 2023
The sphingosine-1-phosphate receptors are a class of G protein-coupled receptors that are targets of the lipid signalling molecule Sphingosine-1-phosphate...12 KB (1,266 words) - 08:05, 18 August 2023
Siponimod, sold under the brand name Mayzent, is a selective sphingosine-1-phosphate receptor modulator for oral use that is used for multiple sclerosis...11 KB (798 words) - 14:37, 24 April 2024
muscle contraction. When transmural pressure increases, sphingosine kinase 1 phosphorylates sphingosine to S1P, which binds to the S1P2 receptor in plasma...37 KB (4,738 words) - 19:39, 25 June 2024- Alternatively, palmitoyl-CoA is used as a substrate in the biosynthesis of sphingosine (this biosynthetic pathway does not require transfer into the mitochondria)...7 KB (600 words) - 14:58, 27 March 2024
- have dinner with a group of her scientist friends who speculate that sphingosine kinase could lead to a cure for cancer. As a result, the President demands...37 KB (1,673 words) - 08:46, 27 June 2024
Opaganib (ABC294640) is a drug which acts as an inhibitor of the enzyme sphingosine kinase 2. It is under development as a potential treatment agent for several...2 KB (109 words) - 09:44, 23 March 2024
- and growth arrest. Sphingosine is capable of directly inhibiting protein kinase C, along with other effects on various protein kinases in vitro. Additionally