Srinivas Aluru
Srinivas Aluru | |
|---|---|
string algorithms | |
| Institutions | Iowa State University Georgia Institute of Technology |
| Thesis | Distribution-independent hierarchical N-body methods |
| Doctoral advisor | John Gustafson, G.M. Prabhu |
Srinivas Aluru is a professor in the
parallel algorithms and applications, interdisciplinary research in bioinformatics and computational biology, and particularly the intersection of these two fields.[3][4]
Education
Aluru completed his B.Tech in computer science at the
Indian Institute of Technology Madras in the year 1989. He then received M.S. and Ph.D. degrees in computer science in 1991 and 1994, both from Iowa State University. His doctoral thesis was "Distribution-independent hierarchical N-body methods”.[1]
Career and research
Aluru began his career in 1991 as a research assistant at
Computational Science and Engineering at Georgia Institute of Technology.[1]
Aluru's research focus has centered around contributions to
parallel algorithms and bioinformatics, particularly genomics. He pioneered the development of parallel methods in computational biology, and development of algorithms and software for high-throughput DNA sequencing analysis and its applications. In this context, some of his group's work led to the development of fundamental string algorithms, particularly for constructing suffix arrays and algorithms for approximate sequence matching. He also solved the open problem of computing string edit distance or biological sequence alignments in optimal time and space. He collaborated with domain scientists on several high impact projects, including sequencing of the maize genome, finding novel genes in maize, and uncovering genetic mechanisms that underlie growth and drought response in plants.[5]
An early pioneer in big data, Aluru led one of the eight inaugural mid-scale NSF-NIH Big Data projects awarded in the first round of federal big data investments in 2012. He has contributed to NITRD and OSTP led white house workshops, and NSF and DOE led efforts to create and nurture big data research. He led the efforts to create the NSF South Big Data Regional Innovation Hub,[6] that nurtures big data partnerships between organizations in the 16 U.S. Southern States and Washington, D.C.
Awards
- Fellow, American Association for the Advancement of Science[7]
- Fellow, Institute for Electrical and Electronics Engineers (IEEE) and IEEE Computer Society[1]
Selected publications
- Schnable, Patrick S.; Ware, Doreen; Fulton, Robert S.; Stein, Joshua C.; Wei, Fusheng; Pasternak, Shiran; Liang, Chengzhi; Zhang, Jianwei; Fulton, Lucinda (2009-11-20). "The B73 Maize Genome: Complexity, Diversity, and Dynamics". Science. 326 (5956): 1112–1115. S2CID 21433160.
- Ko, Pang; Aluru, Srinivas (2003-06-25). "Space Efficient Linear Time Construction of Suffix Arrays". Combinatorial Pattern Matching. Lecture Notes in Computer Science. Vol. 2676. Springer, Berlin, Heidelberg. pp. 200–210. ISBN 978-3540448884.
- Huang, Xiaoqiu; Wang, Jianmin; Aluru, Srinivas; Yang, Shiaw-Pyng; Hillier, LaDeana (2003-09-01). "PCAP: A Whole-Genome Assembly Program". Genome Research. 13 (9): 2164–2170. PMID 12952883.
- Kim, Dong Kyue; Sim, Jeong Seop; Park, Heejin; Park, Kunsoo (2003-06-25). "Linear-Time Construction of Suffix Arrays". Combinatorial Pattern Matching. Lecture Notes in Computer Science. Vol. 2676. Springer, Berlin, Heidelberg. pp. 186–199. ISBN 978-3540448884.
- Yu, Xiaofei; Li, Lei; Zola, Jaroslaw; Aluru, Maneesha; Ye, Huaxun; Foudree, Andrew; Guo, Hongqing; Anderson, Sarah; Aluru, Srinivas (2011-02-01). "A brassinosteroid transcriptional network revealed by genome-wide identification of BESI target genes in Arabidopsis thaliana". The Plant Journal. 65 (4): 634–646. PMID 21214652.
- Aluru, Srinivas (2005-12-21). Handbook of Computational Molecular Biology. CRC Press. ISBN 9781420036275.
- Yang, X.; Chockalingam, S. P.; Aluru, S. (2013-01-01). "A survey of error-correction methods for next-generation sequencing". Briefings in Bioinformatics. 14 (1): 56–66. PMID 22492192.
- Aluru, Srinivas (2005). "Space efficient linear time construction of suffix arrays". Journal of Discrete Algorithms. 3 (2–4): 143–156. .
- Yang, X.; Dorman, K. S.; Aluru, S. (2010-10-15). "Reptile: representative tiling for short read error correction". Bioinformatics. 26 (20): 2526–2533. PMID 20834037.
- Ott, Michael; Zola, Jaroslaw; Stamatakis, Alexandros; Aluru, Srinivas (2007). "Large-scale maximum likelihood-based phylogenetic analysis on the IBM Blue Gene/L". Proceedings of the 2007 ACM/IEEE conference on Supercomputing - SC '07. p. 1. S2CID 16113442.
- Kalyanaraman, A. (2003-06-01). "Efficient clustering of large EST data sets on parallel computers". Nucleic Acids Research. 31 (11): 2963–2974. PMID 12771222.
- Rajko, S.; Aluru, S. (December 2004). "Space and time optimal parallel sequence alignments". IEEE Transactions on Parallel and Distributed Systems. 15 (12): 1070–1081. S2CID 1183248.
References
Scholia has an author profile for Srinivas Aluru.
- ^ a b c d "Srinivas Aluru's Home". www.cc.gatech.edu. Retrieved 2017-12-03.
- ^ "Georgia Tech Meets Big Data Challenges by Uniting Under New Institute". www.news.gatech.edu. Retrieved 2017-12-03.
- ^ "NSF Announces Interagency Progress on Administration's Big Data Initiative | NSF - National Science Foundation". www.nsf.gov. Retrieved 2017-12-03.
- ^ "News - Video - Srinivas Aluru of Iowa State University works at the intersection of the life sciences and big data. | NSF - National Science Foundation". www.nsf.gov. Retrieved 2017-12-03.
- ^ "Researchers detail genetic mechanisms that govern growth and drought response in plants". Retrieved 2017-12-03.
- ^ "Georgia Tech and UNC's RENCI to Lead Major Effort that Applies Big Data Solutions to Regional Challenges | College of Computing". www.cc.gatech.edu. Retrieved 2017-12-03.
- ^ "Aluru, Srinivas". AAAS - The World's Largest General Scientific Society. 2016-08-29. Retrieved 2017-12-03.
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