U.S. Route 45W

United States Numbered Highway in West Tennessee, connecting Jackson with South Fulton via Humboldt, Trenton, Rutherford, and Union City. For the majority of its length, it runs concurrently with unsigned State Route 5 (SR 5).^[1]

US 79 Bypass, and they leave Humboldt head north through farmland. US 45W/SR 5 then pass through Fruitland, where it has an intersection with SR 420 before passing through rural areas. It then enters Trenton at an intersection with SR 457 and SR 367, where US 45W/SR 5 turn right to follow a 2-lane bypass of downtown on the eastern side. The highway becomes concurrent with SR 54 and an intersection with SR 186 in a business district before having an intersection with SR 77 and SR 104, where it becomes concurrent with SR 77 and crosses the North Fork of the Forked Deer River, in a more rural part of town. SR 54 then splits off before the highway curves to the west to have another intersection with SR 367. US 45W/SR 5/SR 77 then widen to a 4-lane divided highway to curve back northward and leave Trenton. They wind their way north through farmland to pass through Dyer, where it bypasses the town on its west side, to have an interchange with SR 185, where SR 77 splits off and goes west. US 45W/SR 5 continue north to pass through Rutherford, where it bypasses the town on its west side, and has an interchange with SR 105. US 45W/SR 5 then narrows to 2-lanes as it has an intersection with its former alignment just before entering Kenton and crossing into Obion County.^[3]

SR 3, where US 45W splits from SR 22 and heads northeast along US 51/SR 3 as a 4-lane freeway. 2 miles (3.2 km) northeast of Union City, US 51/US 45W has a semi-directional T interchange with the SR 690 (Future I-69) freeway. They then have another interchange with SR 214 to enter South Fulton before arriving at an interchange with US 45E/SR 215, where US 45W and US 45E merge to form mainline US 45.^[4]