User:Mr. Ibrahem/Acute myeloid leukemia
| Acute myeloid leukemia | |
|---|---|
| Other names | Acute myelogenous leukemia, acute nonlymphocytic leukemia (ANLL), acute myeloblastic leukemia, acute granulocytic leukemia Five-year survival ~27% (US)[2] |
| Frequency | 1 million (2015)[4] |
| Deaths | 147,100 (2015)[5] |
Acute myeloid leukemia (AML) is a
blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production.[1] Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection.[1] Occasionally, spread may occur to the brain, skin, or gums.[1] As an acute leukemia, AML progresses rapidly and is typically fatal within weeks or months if left untreated.[1][6]
bone marrow aspiration and specific blood tests.[3] AML has several subtypes for which treatments and outcomes may vary.[1]
AML typically is initially treated with
genetic mutations present within the cancer cells may guide therapy, as well as determine how long that person is likely to survive.[3]
In 2015, AML affected about one million people and resulted in 147,000 deaths globally.[4][5] It most commonly occurs in older adults.[2] Males are affected more often than females.[2] Five-year survival rate are about 35% in people under 60 years old and 10% in people over 60 years old.[3] Older people whose health is too poor for intensive chemotherapy have a typical survival of 5–10 months.[3] It accounts for roughly 1.8% of cancer deaths in the United States.[2]
References
- ^ a b c d e f g h i j k l m "Adult Acute Myeloid Leukemia Treatment". National Cancer Institute. 6 March 2017. Archived from the original on 23 October 2018. Retrieved 19 December 2017.
- ^ a b c d e "Acute Myeloid Leukemia – Cancer Stat Facts". NCI. Archived from the original on 28 July 2017. Retrieved 10 May 2017.
- ^ S2CID 40314260.
- ^ PMID 27733282.
- ^ PMID 27733281.
- ISBN 9781451116045. Archivedfrom the original on 27 August 2021. Retrieved 25 May 2020.