User:Mr. Ibrahem/Lemierre syndrome

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Lemierre syndrome
Other namesLemierre's syndrome,
infectious disease[1]
SymptomsEarly: Fever, neck pain[1]
Later:
Frequency1 to 6 per million people per year[1][3]

Lemierre syndrome is infectious thrombophlebitis of the internal jugular vein.[2][4] Initial symptoms include fever, neck pain, and neck swelling.[1][2] Generally the pain and swelling is one sided and occurs at the angle of the jaw.[2] Later symptoms may include pneumonia, pleural empyema, sepsis, brain abscess, and septic emboli.[1][2] Complications may include septic shock, disseminated intravascular coagulation, and end organ failure.[2]

It most commonly occurs follow a

lateral pharyngeal space.[2] Diagnosis is generally based on symptoms and ultrasound or CT scan; as culture results take around a week.[1]

Treatment is generally with around two weeks of

abscesses.[3][1] With treatment, the risk of death is 5 to 18%.[2] Before the availability of antibiotics, the risk of death was 90% over about 2 weeks.[3][1]

Lemierre's syndrome occurs in 1 to 6 per million people per year.[1][3] Young adults males are most commonly affected.[1] In 1936, André Lemierre described 20 cases where throat infections was followed by sepsis.[5][2]

References