User:Mr. Ibrahem/Prasugrel

Source: Wikipedia, the free encyclopedia.
Mr. Ibrahem/Prasugrel
Clinical data
Trade namesEffient, Efient
AHFS/Drugs.comMonograph
MedlinePlusa609027
License data
Pregnancy
category
  • AU: B1
Platelet inhibitor (P2Y12)[1]
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • US: ℞-only
  • EU: Rx-only
Pharmacokinetic data
Bioavailability≥79%
Protein bindingActive metabolite: ~98%
Elimination half-life~7 h (range 2 h to 15 h)
ExcretionUrine (~68% inactive metabolites); feces (27% inactive metabolites)
Identifiers
  • (RS)-5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
    tetrahydrothieno[3,2-c]pyridin-2-yl acetate
Chemical and physical data
JSmol)
  • CC(=O)Oc1cc2c(s1)CCN(C2)C(c3ccccc3F)C(=O)C4CC4
  • InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3 checkY
  • Key:DTGLZDAWLRGWQN-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Prasugrel, sold under the brand name Effient and Efient, is a medication used to prevent blood clots in people with acute coronary syndrome (ACS) who getting percutaneous coronary intervention (PCI).[2] It is used together with aspirin.[2] It is taken by mouth.[2]

Common side effects include bleeding.

platelet inhibitor of the P2Y12 platelet adenosine diphosphate (ADP)-receptor inhibitor type.[1]

Prasugrel was approved for use in Europe and the United States in 2009.

NHS about £6 as of 2021.[4] This amount in the United States is about 30 USD.[5] It is no longer available in Canada as of 2020.[6]

References

  1. ^ a b c d e "DailyMed - PRASUGREL- prasugrel hydrochloride tablet, film coated". dailymed.nlm.nih.gov. Archived from the original on 30 October 2021. Retrieved 29 October 2021.
  2. ^ a b c d e "Efient". Archived from the original on 26 February 2021. Retrieved 29 October 2021.
  3. ^ "Prasugrel Monograph for Professionals". Drugs.com. Archived from the original on 27 February 2021. Retrieved 29 October 2021.
  4. ^
    ISBN 978-0857114105
    .
  5. ^ "Prasugrel Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 19 April 2021. Retrieved 29 October 2021.
  6. ISSN 2589-790X
    .
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