Yoshitaka Fujii

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Yoshitaka Fujii
Born (1960-04-19) 19 April 1960 (age 64)
NationalityJapanese
Alma materTokai University
Tokyo Medical and Dental University
Known forFalsifying scientific data
Scientific career
FieldsAnesthesiology
InstitutionsTokyo Medical and Dental University
University of Tsukuba
Toho University

Yoshitaka Fujii (藤井 善隆, Fujii Yoshitaka) is a Japanese researcher in

scientific papers, of which 183[1] have been retracted.[2][3]

Summary of professional career

Fujii graduated from

Ph.D. in 1991.[5] During his career, he worked at institutions including Tokyo Medical and Dental University, the University of Tsukuba, and Toho University.[2] According to an online CV, he spent two years in Canada as a research fellow at Royal Victoria Hospital, McGill University, before assuming a faculty position at the University of Tsukuba Institute of Clinical Medicine in 1997. He joined the faculty of Toho University in 2005. The main subject of his research publications was clinical trials of medications to treat the nausea and vomiting that often occurs after surgery.[4]

In February 2012, after initial investigations into allegations of scientific misconduct, he was dismissed from his position as associate professor of anesthesiology in the Toho University Faculty of Medicine.[6]

Research misconduct

Fujii apparently began publishing falsified data in 1993.

U.S. Food and Drug Administration, the Japanese Pharmaceuticals and Medical Devices Agency, and the Japanese Society of Anesthesiologists to alert them to the possible unreliability of Fujii's results, but did not receive any response.[4] No institutional review of Fujii's research was requested and journals continued to accept new papers submitted by Fujii.[4][8] The editors of Anesthesia & Analgesia did not follow up on the fraud allegations against Fujii until about 2010, when its editor and the editors of several other journals began a coordinated investigation into the integrity of Fujii's scientific publications after the editor of the journal Anaesthesia voiced new concerns.[4][8] In March 2012, the editor of Anesthesia & Analgesia acknowledged that the journal's response to the allegations made in 2000 had been "inadequate".[8]

Two analyses of some of Fujii's publications were released in March 2012. On 7 March, Toho University reported finding that although nine of Fujii's publications were about clinical studies described as having been conducted at

statistical methods to evaluate whether the published distributions of various variables were consistent with the distributions that could be expected to result from random chance. He found that many of the data sets were "extremely unlikely to have arisen by chance", noting that many of the distributions had "likelihoods that are infinitesimally small", citing a calculated probability of 6.78 × 10−9, or about 1 in 150 million. Accordingly, he recommended that data published by Fujii should be "excluded from meta-analyses or reviews" until such time that the unlikely results could be satisfactorily explained.[10]

In April, the editors of 23 scientific journals made a public request for an investigation of Fujii's research by the seven Japanese institutions named as affiliations in his published papers.

laboratory notebooks, patient records, and other raw data from his studies.[2] On 29 June 2012, the committee reported finding that a total of 172 papers contained fabricated data. Of these, 126 papers were determined to have been "totally fabricated". The report stated: "It is as if someone sat at a desk and wrote a novel about a research idea." The committee found that three of the 212 papers were valid. For 37 of the 212 papers, the committee was unable to determine whether data had been fabricated.[2]

The investigators observed that Fujii seemed to have been deliberately ambiguous about details such as the dates of the studies and the names of the institutions where they were conducted, apparently to reduce the possibility that his fraud would be detected. Also, by listing co-authors from institutions other than his current employer, he conveyed the impression that the papers described studies done at multiple hospitals.[12] Several scientists listed as co-authors were not aware that Fujii had included their names on his papers; two named co-authors said that their signatures had been forged on a cover letter submitting the paper to the journal.[2][12] Retraction Watch suggested that the supposed co-authors might not have been aware that their names had been misused because the papers had received few citations.[2][13] Investigators found that one of Fujii's co-authors, Hidenori Toyooka, who collaborated with Fujii on "dozens" of papers, may have been aware of the deception.[12]

As of 2023, 183 of Fujii's research publications have been retracted, and 47 other papers have received an expression of concern.[1] According to Retraction Watch, Fujii has the second most retractions of scientific papers by a single author as of September 2023.[14] He was at the top of Retraction Watch's leaderboard until July 2023, when he was surpassed by German anesthesiologist Joachim Boldt.[15]

See also

References

  1. ^ a b "Retraction Watch Database". Retraction Watch. Center for Scientific Integrity. Archived from the original on 2020-06-12. Retrieved 2023-01-06.
  2. ^ a b c d e f g h Normile, Dennis (2 July 2012), "A New Record for Retractions?", Science Insider, American Association for the Advancement of Science, archived from the original on July 5, 2012
  3. ^ Marcus, Author Adam (2023-07-12). "The new retraction record holder is a German anesthesiologist, with 184". Retraction Watch. Archived from the original on 2023-08-12. Retrieved 2023-08-03. {{cite web}}: |first= has generic name (help)
  4. ^ a b c d e f g h Marcus, Adam (7 March 2012). "Japanese PONV Researcher Probed in Sweeping Research Fraud Case". Anesthesiology News. Archived from the original on 19 November 2023. Retrieved 3 July 2012.
  5. ^ Fujii, Yoshitaka (1991) Diaphragmatic fatigue and its recovery are influenced by cardiac output. Archived 2017-10-11 at the Wayback Machine Dissertation, Tokyo Medical and Dental University.
  6. ^ a b Kuroda, Masaru. "Disciplinary Decision concerning Dr. Yoshitaka Fujii". Toho University Faculty of Medicine. Archived from the original on 16 June 2012. Retrieved 3 July 2012.
  7. ^
    PMID 10735823. Archived
    from the original on 2012-07-23. Retrieved 2012-07-03.
  8. ^ a b c d e Shafer, Steven L. (March 7, 2012). "To our readers" (PDF). Anesthesia & Analgesia. Archived (PDF) from the original on August 31, 2012. Retrieved July 3, 2012.
  9. S2CID 20892818
    .
  10. ^
    PMID 22404311
    .
  11. ^ Akst, Jef (3 July 2012). "Anesthesiologist Fabricates 172 Papers". The Scientist. Archived from the original on 24 July 2012. Retrieved 3 July 2012.
  12. ^ a b c Marcus, Adam (July 2, 2012). "Report: Japanese Anesthesiologist Fabricated Data in 172 Studies; Inquiry into PONV researcher Yoshitaka Fujii, MD, finds only three of 212 papers free of fraud". Anesthesiology News. Retrieved July 26, 2012.[dead link]
  13. ^ "Three more Fujii papers fall for lack of IRB approval". Retraction Watch. 18 June 2012. Archived from the original on 7 July 2012. Retrieved 3 July 2012.
  14. ^ "The Retraction Watch Leaderboard". Retraction Watch. Center for Scientific Integrity. 16 June 2015. Archived from the original on 2019-05-31. Retrieved 2023-01-06.
  15. ^ Marcus, Adam (12 July 2023). "The new retraction record holder is a German anesthesiologist, with 184". Retraction Watch. Archived from the original on 12 August 2023. Retrieved 24 November 2023.

External links

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