7-OH-DPAT

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7-OH-DPAT
Kekulé, skeletal formula of 7-OH-DPAT
Names
IUPAC name
7-Hydroxy-N,N-dipropyl-2-aminotetralin[citation needed]
Systematic IUPAC name
7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol[1]
Identifiers
3D model (
JSmol
)
Abbreviations 7-OH-DPAT
ChEMBL
ChemSpider
IUPHAR/BPS
MeSH 7-Hydroxy-2-N,N-dipropylaminotetralin
UNII
  • InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 checkY
    Key: BLYMJBIZMIGWFK-UHFFFAOYSA-N checkY
  • InChI=1/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3
    Key: BLYMJBIZMIGWFK-UHFFFAOYAH
  • CCCN(CCC)C1CCc2ccc(O)cc2C1
  • CCCN(CCC)C1CCC2=C(C1)C=C(O)C=C2
Properties
C16H25NO
Molar mass 247.382 g·mol−1
log P 3.653
Acidity (pKa) 10.389
Basicity (pKb) 3.608
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

7-OH-DPAT is a synthetic compound that acts as a

serotonin receptors, unlike its structural isomer 8-OH-DPAT.[5][6][7] 7-OH-DPAT is self-administered in several animal models, and is used to study its addiction effects to cocaine.[8][9][10][11][12]

See also

References

  1. ^ "7-hydroxy-2-N,N-dipropylaminotetralin - PubChem Public Chemical Database". The PubChem Project. USA: National Center for Biotechnology Information.
  2. S2CID 20846810
    .
  3. PMID 1518841
    .
  4. PMID 8759022
    .
  5. PMID 2959776
    .
  6. PMID 8078492
    .
  7. PMID 11472307
    .
  8. PMID 7589197
    .
  9. S2CID 27951018
    .
  10. S2CID 10593118
    .
  11. S2CID 2959198
    .
  12. PMID 22470105
    .
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