Angelika Gründling

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Angelika Gründling
Born1972 (age 51–52)
Alma materUniversity of Vienna
Scientific career
InstitutionsImperial College London
University of Chicago
Harvard Medical School

Angelika Gründling (born 1972) is an Austrian microbiologist who is Professor of Molecular Microbiology at Imperial College London. Her research considers Staphylococcus aureus, nucleotide signalling and cell wall biosynthesis. She was elected a Fellow of the European Academy of Microbiology in 2018.

Early life and education

Gründling completed her undergraduate studies at the University of Vienna.[1] She conducted doctoral research with Ry Young at Texas A&M University.[citation needed] She moved to Harvard Medical School, where she studied the mobility of Listeria monocytogenes supported by an Erwin Schrödinger postdoctoral fellowship. There she investigated the motility of the flagellum in bacterial pathogen Listeria monocytogenes. Gründling moved to the Schneewind laboratory at the University of Chicago, where she investigated the cell wall of Staphylococcus aureus.[2] As a postdoctoral researcher, she discovered the enzyme needed to make lipoteichoic acid, lipoteichoic acid synthase.[3]

Research and career

In 2007, Gründling joined

Gram-positive bacterial pathogens. She studies the synthesis of cell walls and various pathways for nucleotide signalling in Staphylococcus aureus and Listeria monocytogenes
.

She studied membrane function at Harvard Medical School.[4] In particular, Gründling was interested in the mechanisms that underpin the growth of the bacterial membrane.[4] Bacteria are composted of a phospholipid bilayer, mainly composed of phosphatidylglycerol, the enzymes of which have barely been characterised. She used genetic methods to unravel the mechanisms behind lipid transfer within the membrane and to identify the proteins required for membrane construction.[4]

Awards and honours

Selected publications

  • Rebecca M Corrigan; James C Abbott; Heike Burhenne; Volkhard Kaever; Angelika Gründling (1 September 2011). "c-di-AMP is a new second messenger in Staphylococcus aureus with a role in controlling cell size and envelope stress".
    Wikidata Q34016233
    .
  • Matthew G Percy; Angelika Gründling (5 May 2014). "Lipoteichoic acid synthesis and function in gram-positive bacteria".
    Wikidata Q38211157
    .
  • Rebecca M Corrigan; Angelika Gründling (1 July 2013). "Cyclic di-AMP: another second messenger enters the fray".
    Wikidata Q38118107
    .

References

  1. .
  2. ^ "FEMS Expert: Prof Angelika Gründling". FEMS. Retrieved 2024-03-03.
  3. ^ a b "Understanding the Building Blocks of Bacteria". 2012-09-12.
  4. ^ a b c "Angelika Grundling". Bernhardt lab. Retrieved 2024-03-03.
  5. ^ a b "Honours and Memberships - Professor Angelika Gründling". www.imperial.ac.uk. Retrieved 2024-03-03.
  6. ^ "Fellows". FEMS. Retrieved 2024-03-03.