Deconvolution

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Before and after deconvolution of an image of the lunar crater Copernicus using the Richardson-Lucy algorithm.

In

image processing. For example, it may be possible to recover the original signal after a filter (convolution) by using a deconvolution method with a certain degree of accuracy.[1] Due to the measurement error of the recorded signal or image, it can be demonstrated that the worse the signal-to-noise ratio
(SNR), the worse the reversing of a filter will be; hence, inverting a filter is not always a good solution as the error amplifies. Deconvolution offers a solution to this problem.

The foundations for deconvolution and

time-series analysis were largely laid by Norbert Wiener of the Massachusetts Institute of Technology in his book Extrapolation, Interpolation, and Smoothing of Stationary Time Series (1949).[2] The book was based on work Wiener had done during World War II but that had been classified at the time. Some of the early attempts to apply these theories were in the fields of weather forecasting and economics
.

Description

In general, the objective of deconvolution is to find the solution f of a convolution equation of the form:

Usually, h is some recorded signal, and f is some signal that we wish to recover, but has been convolved with a filter or distortion function g, before we recorded it. Usually, h is a distorted version of f and the shape of f can't be easily recognized by the eye or simpler time-domain operations. The function g represents the impulse response of an instrument or a driving force that was applied to a physical system. If we know g, or at least know the form of g, then we can perform deterministic deconvolution. However, if we do not know g in advance, then we need to estimate it. This can be done using methods of statistical estimation or building the physical principles of the underlying system, such as the electrical circuit equations or diffusion equations.

There are several deconvolution techniques, depending on the choice of the measurement error and deconvolution parameters:

Raw deconvolution

When the measurement error is very low (ideal case), deconvolution collapses into a filter reversing. This kind of deconvolution can be performed in the Laplace domain. By computing the Fourier transform of the recorded signal h and the system response function g, you get H and G, with G as the transfer function. Using the Convolution theorem,

where F is the estimated Fourier transform of f. Finally, the inverse Fourier transform of the function F is taken to find the estimated deconvolved signal f. Note that G is at the denominator and could amplify elements of the error model if present.

Deconvolution with noise

In physical measurements, the situation is usually closer to

In this case ε is

noise that has entered our recorded signal. If a noisy signal or image is assumed to be noiseless, the statistical estimate of g will be incorrect. In turn, the estimate of ƒ will also be incorrect. The lower the signal-to-noise ratio, the worse the estimate of the deconvolved signal will be. That is the reason why inverse filtering the signal (as in the "raw deconvolution" above) is usually not a good solution. However, if at least some knowledge exists of the type of noise in the data (for example, white noise), the estimate of ƒ can be improved through techniques such as Wiener deconvolution
.

Applications

Seismology

The concept of deconvolution had an early application in

, where t represents recording time. Thus, our convolution equation is

The seismologist is interested in e, which contains information about the Earth's structure. By the convolution theorem, this equation may be Fourier transformed to

in the frequency domain, where is the frequency variable. By assuming that the reflectivity is white, we can assume that the power spectrum of the reflectivity is constant, and that the power spectrum of the seismogram is the spectrum of the wavelet multiplied by that constant. Thus,

If we assume that the wavelet is minimum phase, we can recover it by calculating the minimum phase equivalent of the power spectrum we just found. The reflectivity may be recovered by designing and applying a Wiener filter that shapes the estimated wavelet to a Dirac delta function (i.e., a spike). The result may be seen as a series of scaled, shifted delta functions (although this is not mathematically rigorous):

where N is the number of reflection events, are the reflection coefficients, are the reflection times of each event, and is the Dirac delta function.

In practice, since we are dealing with noisy, finite bandwidth, finite length, discretely sampled datasets, the above procedure only yields an approximation of the filter required to deconvolve the data. However, by formulating the problem as the solution of a Toeplitz matrix and using Levinson recursion, we can relatively quickly estimate a filter with the smallest mean squared error possible. We can also do deconvolution directly in the frequency domain and get similar results. The technique is closely related to linear prediction.

Optics and other imaging

Example of a deconvolved microscope image.

In optics and imaging, the term "deconvolution" is specifically used to refer to the process of reversing the

optical distortion that takes place in an optical microscope, electron microscope, telescope, or other imaging instrument, thus creating clearer images. It is usually done in the digital domain by a software algorithm, as part of a suite of microscope image processing techniques. Deconvolution is also practical to sharpen images that suffer from fast motion or jiggles during capturing. Early Hubble Space Telescope images were distorted by a flawed mirror
and were sharpened by deconvolution.

The usual method is to assume that the optical path through the instrument is optically perfect, convolved with a

mathematical function that describes the distortion in terms of the pathway a theoretical point source of light (or other waves) takes through the instrument.[3] Usually, such a point source contributes a small area of fuzziness to the final image. If this function can be determined, it is then a matter of computing its inverse
or complementary function, and convolving the acquired image with that. The result is the original, undistorted image.

In practice, finding the true PSF is impossible, and usually an approximation of it is used, theoretically calculated

expectation-maximization algorithms
) can be applied to avoid unrealistic solutions.

When the PSF is unknown, it may be possible to deduce it by systematically trying different possible PSFs and assessing whether the image has improved. This procedure is called

fluorescence microscopy for image restoration, and in fluorescence spectral imaging for spectral separation of multiple unknown fluorophores. The most common iterative algorithm for the purpose is the Richardson–Lucy deconvolution algorithm; the Wiener deconvolution
(and approximations) are the most common non-iterative algorithms.

High Resolution THz image is achieved by deconvolution of the THz image and the mathematically modeled THz PSF. (a) THz image of an integrated circuit (IC) before enhancement; (b) Mathematically modeled THz PSF; (c) High resolution THz image which is achieved as a result of deconvolution of the THz image shown in (a) and the PSF which is shown in (b); (d) High resolution X-ray image confirms the accuracy of the measured values.[5]

For some specific imaging systems such as laser pulsed terahertz systems, PSF can be modeled mathematically.[6] As a result, as shown in the figure, deconvolution of the modeled PSF and the terahertz image can give a higher resolution representation of the terahertz image.

Radio astronomy

When performing image synthesis in radio interferometry, a specific kind of radio astronomy, one step consists of deconvolving the produced image with the "dirty beam", which is a different name for the point spread function. A commonly used method is the CLEAN algorithm.

Biology, physiology and medical devices

Typical use of deconvolution is in tracer kinetics. For example, when measuring a hormone concentration in the blood, its secretion rate can be estimated by deconvolution. Another example is the estimation of the blood glucose concentration from the measured interstitial glucose, which is a distorted version in time and amplitude of the real blood glucose. [7]

Absorption spectra

Deconvolution has been applied extensively to absorption spectra.[8] The Van Cittert algorithm (article in German) may be used.[9]

Fourier transform aspects

Deconvolution maps to division in the

NMR spectroscopy
where the data are recorded in the time domain, but analyzed in the frequency domain. Division of the time-domain data by an exponential function has the effect of reducing the width of Lorentzian lines in the frequency domain.

See also

References

  1. ^ O'Haver, T. "Intro to Signal Processing - Deconvolution". University of Maryland at College Park. Retrieved 2007-08-15.
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  6. ^ Sung, Shijun (2013). Terahertz Imaging and Remote Sensing Design for Applications in Medical Imaging. UCLA Electronic Theses and Dissertations.
  7. PMID 8773311
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