Edward C. Holmes

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Edward C. Holmes
FAA
Holmes in 2017
Born (1965-02-26) 26 February 1965 (age 59)[2]
Alma mater
Known forMolecular Evolution: A Phylogenetic Approach[5]
Awards
Scientific career
Fields
Institutions
ThesisPattern and Process in the Molecular Evolution of the Order Primates (1990)
Academic advisorsAdrian Friday[2]
Websitesydney.edu.au/science/people/edward.holmes.php

Edward Charles Holmes

FAA[6] (born 26 February 1965)[2] is a British evolutionary biologist and virologist. Since 2012, he has been a fellow of the National Health and Medical Research Council (NHMRC) in Australia and professor at the University of Sydney.[4][7][8] He was an honorary visiting professor at Fudan University in Shanghai, China, from 2019-2021.[9]

Education

Holmes was educated at University College London where he received a Bachelor of Science degree in Anthropology in 1986.[2] He then moved to the University of Cambridge where he was awarded a Doctor of Philosophy degree in Zoology in 1990[10][2] for research on molecular evolution in primates supervised by Adrian Friday.[2]

Research and career

Holmes has used

dengue,[16] and enabled more accurate assessments of what types of virus are most likely to emerge in human populations and whether they will evolve human-to-human transmission.[6] His recent research has provided fundamental insights into the breadth and biodiversity of the viral world.[6]

Holmes wrote The Evolution and Emergence of RNA Viruses[17] part of the Oxford Series in Ecology and Evolution edited by Paul H. Harvey and Robert M. May. He also co-authored the textbook Molecular Evolution: A Phylogenetic Approach with Rod Page.[5] Since 1994 he has supervised 31 graduate students.[2]

SARS-CoV-2

Holmes co-authored the publication of the genome sequence of SARS-CoV-2[18][19] and the early descriptions of the disease, working with Zhang Yongzhen from Fudan University to share the first sequencing data from the virus.[20] Holmes has figured prominently in commentary surrounding its origins. In March 2020, he co-authored a letter titled The proximal origins of SARS-CoV-2, published in Nature Medicine,[21] which examined the mutations in the receptor-binding domain and furin cleavage site, and concluded that the virus sequence did not appear to be engineered.[22][23] He co-authored a more-detailed review article in Cell.[24]

The University of Sydney published a statement by Holmes in April that stated, "There is no evidence that SARS-CoV-2, the virus that causes COVID-19 in humans, originated in a laboratory in Wuhan, China", and that all evidence points towards its origin in an animal species.[25] These views were reported in the Financial Times in May 2020.[26]

Institutional affiliations

Before moving to Sydney in 2012, Holmes held academic appointments at various universities in the UK and USA including:

1990–1991 University of California, Davis,[2] postdoctoral researcher supervised by Charles H. Langley.
1991–1993 University of Edinburgh,[2] postdoc funded by the UK Medical Research Council (MRC).[2][11]
1993–2004 University of Oxford[2] where he was a Fellow of New College, Oxford and St Catherine's College, Oxford
2005–2012 Pennsylvania State University, Full Professor of Biology[2]

His research has been funded by the

Rhodes Trust, Wellcome Trust, United States National Institutes of Health (NIH), National Science Foundation (NSF), Australian Research Council, and Australian National Health and Medical Research Council (NHMRC).[2][1][27]

Awards and honours

Holmes was elected a

SARSCov2 genome.[29] In November 2021 he was awarded the Prime Minister's Prize for Science.[30]
He was the recipient of the 2024 Croonian Medal and Lecture, awarded by the Royal Society.[31]

Personal life

Holmes lists his recreations as Whale Beach, New South Wales, electric guitars, and Aston Villa Football Club.[32]

See also

References

Scholia has an author profile for Edward C. Holmes.
  1. ^
    ORCID 0000-0001-9596-3552
  2. ^ a b c d e f g h i j k l m n o Holmes, Eddie (2020). "Edward C. Holmes – Curriculum Vitae". profiles.sydney.edu.au. University of Sydney. Archived from the original on 8 August 2017.
  3. ^ a b "Fellowships and training centres accelerate research capacity". University of Sydney. 5 June 2017. Retrieved 21 January 2018.
  4. ^ a b Edward C. Holmes publications indexed by Google Scholar Edit this at Wikidata
  5. ^
    OCLC 47011609
    .
  6. ^ a b c d e f "Edward Holmes". RoyalSociety.org. London: Royal Society. 2017. Archived from the original on 11 May 2017. One or more of the preceding sentences incorporates text from the royalsociety.org website where:

    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --"Royal Society Terms, conditions and policies". Archived from the original on 11 November 2016. Retrieved 9 March 2016.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  7. ^ Edward C. Holmes publications indexed by the Scopus bibliographic database. (subscription required)
  8. ^ Edward C. Holmes publications from Europe PubMed Central
  9. ^ "Staff Profile". The University of Sydney. Retrieved 9 July 2021.
  10. ProQuest 1771542055
    .
  11. ^
    S2CID 1573464
    .
  12. PMID 8245854
    .
  13. PMID 24130481. Open access icon
  14. PMID 18418375. Closed access icon
  15. S2CID 28756735
    .
  16. PMID 12797969
    . (subscription required)
  17. ISBN 9780199211135
    .
  18. PMID 32007145
    .
  19. PMID 32220310
    .
  20. PMID 32015508
    .
  21. PMID 32284615
    .
  22. ^ Spinney, Laura (28 March 2020). "Is factory farming to blame for coronavirus?". the Guardian. Retrieved 1 November 2020.
  23. ^ Mannix, Liam (24 April 2020). "Coronavirus Australia: Scientists dispel theory COVID-19 escaped from lab". The Sydney Morning Herald. Retrieved 1 November 2020.
  24. PMID 34480864
    .
  25. The University of Sydney
    . Retrieved 1 November 2020.
  26. ^ Weinland, Don; Manson, Katrina (5 May 2020). "How a Wuhan lab became embroiled in a global coronavirus blame game". Financial Times. Retrieved 1 November 2020.
  27. ^ "Professor Holmes driven by the pursuit of scientific truth". The University of Sydney. Retrieved 15 September 2020.
  28. ^ Aubusson, Kate (26 October 2020). "Virus rebel Professor Edward Holmes named NSW Scientist of the Year". The Sydney Morning Herald. Retrieved 26 October 2020.
  29. ^ "The Research Symbiont Awards". ResearchSymbionts.org. 8 January 2021. Retrieved 1 May 2021.
  30. ^ "Prime Minister's Prizes for Science 2021". Department of Industry, Science, Energy and Resources. 3 November 2021. Archived from the original on 4 November 2021. Retrieved 3 November 2021.
  31. ^ "Croonian Medal and Lecture winner 2024". 20 August 2023. Retrieved 31 August 2023.
  32. ^ Fallon, Bailey (2015). "Meet our Editors: An interview with Edward Holmes". blogs.royalsociety.org. Archived from the original on 19 November 2016.
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